Estradiol Cypionate

Estradiol Cypionate

SCHEMBL41551

C[C@]12CC[C@@H]3c4ccc(O)cc4CC[C@H]3[C@@H]1CC[C@@H]2OC(=O)CCC1CCCC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ESR1

The experimentally established mechanism targets of Estradiol Cypionate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 known ✓ P03372 4/20 1.00
LMNA P02545 7/20 1.00
MAPT P10636 7/20 1.00
CYP3A4 P08684 6/20 1.00
KMT2A Q03164 6/20 1.00
MEN1 O00255 5/20 1.00
TP53 P04637 4/20 1.00
MAPK1 P28482 3/20 1.00
PGR P06401 2/20 1.00
ADORA3 P0DMS8 2/20 1.00
AR P10275 2/20 1.00
PTGS1 P23219 2/20 1.00
PDE3A Q14432 2/20 1.00
CYP2C19 P33261 2/20 1.00
PDE4A P27815 1/20 1.00
SMN1; SMN2 Q16637 3/20 0.78
HIF1A Q16665 2/20 0.78
ALOX15 P16050 3/20 0.77
POLB P06746 1/20 0.77
CHRM1 P11229 1/20 0.77

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Estradiol Cypionate SCHEMBL29404977 1.00 LMNA (1.00) LMNAMAPTCYP3A4KMT2AMEN1
Estradiol Cypionate SCHEMBL20130822 1.00 LMNA (1.00) LMNAMAPTCYP3A4KMT2AMEN1
Estradiol Cypionate SCHEMBL19236258 1.00 LMNA (1.00) LMNAMAPTCYP3A4KMT2AMEN1
Estradiol Cypionate SCHEMBL12754433 1.00 LMNA (1.00) LMNAMAPTCYP3A4KMT2AMEN1
Estradiol Cypionate SCHEMBL28333106 1.00 LMNA (1.00) LMNAMAPTCYP3A4KMT2AMEN1
Estradiol Cypionate SCHEMBL6195927 0.96 LMNA (0.92) LMNAMAPTCYP3A4KMT2AMEN1
Estradiol Cypionate SCHEMBL3199191 0.93 LMNA (0.87) LMNAMAPTCYP3A4KMT2AMEN1
Estradiol Cypionate SCHEMBL15532173 0.92 LMNA (0.85) LMNAMAPTCYP3A4KMT2AMEN1
SCHEMBL4649449 0.90 MAPT (0.82) LMNAMAPTCYP3A4KMT2AMEN1
SCHEMBL32662059 0.90 LMNA (0.82) LMNAMAPTCYP3A4KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4418 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260076872-A1 POLYMER VIALS WITH SUBSTANTIALLY FLAT BOTTOMS AND INJECTION STRETCH BLOW MOLDING METHODS FOR MAKING THE SAME SIO2 MEDICAL PRODUCTS LLC (US) 2026-03-19 US claimed
US-20250242092-A1 SiOx BARRIER FOR PHARMACEUTICAL PACKAGE AND COATING PROCESS SIO2 MEDICAL PRODUCTS INC (US) 2025-07-31 US claimed
EP-3426327-B1 NEEDLELESS INJECTION DEVICE EQUIPPED WITH AN IMPROVED INJECTION NOZZLE CROSSJECT (FR) 2025-07-09 EP claimed
US-12310928-B2 Enthesis healing UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2025-05-27 US claimed
EP-4531594-A1 PREVENTION OF ESTRUS IN SOW AND RUMINANTS Insigna Inc. (US) 2025-04-09 EP claimed
US-12257371-B2 SiOx barrier for pharmaceutical package and coating process SIO2 MEDICAL PRODUCTS, LLC (US) 2025-03-25 US claimed
US-20240315965-A1 COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS Natural Extraction Systems, LLC (US) 2024-09-26 US claimed
EP-3863708-B1 MIXED IONIC CONDUCTORS AND CORRESPONDING DEVICES, SYSTEMS AND METHODS OF MAKING BATTELLE MEMORIAL INSTITUTE (US) 2024-09-11 EP claimed
US-20240282425-A1 AUTHENTICATION METHODS AND SYSTEMS FOR DISPENSED PRESCRIPTIONS LOW GORDON KEITH (US) 2024-08-22 US claimed
US-11992660-B2 Needleless injection device equipped with an improved injection nozzle CROSSJECT (FR) 2024-05-28 US claimed
US-4948593-A SUSTAINED AND CONTROLLED CONTRACEPTION ALZA CORPORATION (US) 1990-08-14 US claimed
US-4863911-A Method for treating male sexual dysfunction UNIVERSITY OF FLORIDA (US) 1989-09-05 US claimed
EP-0256668-A2 Method for treating male sexual dysfunction UNIVERSITY OF FLORIDA (US) 1988-02-24 EP claimed
EP-0227356-A2 The use of depogen in the treatment of restricted blood circulation CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT. (HU) 1987-07-01 EP claimed
EP-0220844-A2 Use of estrogen-dihydropyridine compounds for weight control UNIVERSITY OF FLORIDA (US) 1987-05-06 EP claimed
US-4629449-A Vaginal dispenser for dispensing beneficial hormone ALZA CORPORATION (US) 1986-12-16 US claimed
US-4617298-A STEROIDS UNIVERSITY OF FLORIDA (US) 1986-10-14 US claimed
US-4402695-A Device for delivering agent in vagina ALZA CORPORATION (US) 1983-09-06 US claimed
US-4383993-A PROGESTERONE, ESTRADIOL AND ESTERS UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) 1983-05-17 US claimed
US-4315925-A MAMMALIAN CONTRACEPTIVES COMPRISING PROGESTERONE AND 17B-ESTRADIOL UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) 1982-02-16 US claimed