Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RELA | Q04206 | 2/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | CHAT | P28329 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL373800 | 0.91 | MAOB (0.41) | RELATRPA1MAOBIDO1MEN1 | |
| SCHEMBL373813 | 0.84 | RELA (0.36) | RELATRPA1MAOBMEN1KMT2A | |
| SCHEMBL373763 | 0.80 | TRPA1 (0.38) | RELATRPA1MAOBMEN1KMT2A | |
| SCHEMBL17451086 | 0.77 | TRPA1 (0.38) | RELATRPA1MAOBIDO1MEN1 | |
| SCHEMBL373430 | 0.76 | MAOB (0.41) | RELATRPA1MAOBIDO1MEN1 | |
| SCHEMBL18380875 | 0.76 | MAOB (0.41) | RELATRPA1MAOBIDO1MEN1 | |
| SCHEMBL373740 | 0.76 | MAOB (0.41) | RELATRPA1MAOBIDO1MEN1 | |
| SCHEMBL1971360 | 0.74 | TRPA1 (0.47) | RELATRPA1MAOBMEN1KMT2A | |
| SCHEMBL1971359 | 0.74 | TRPA1 (0.47) | RELATRPA1MAOBMEN1KMT2A | |
| SCHEMBL2037295 | 0.71 | TRPA1 (0.37) | RELATRPA1MAOBIDO1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1696257-B1 | CONTACT LENS MATERIAL | MENICON CO LTD (JP) | 2012-11-21 | — | — | EP | disclosed |
| US-20090247662-A1 | Contact Lens Material | MATSUMOTO MASAHIRO | 2009-10-01 | — | — | US | disclosed |
| US-20070149699-A1 | Contact lens material | MENICON CO., LTD. (JP) | 2007-06-28 | — | — | US | disclosed |
| EP-1696257-A1 | CONTACT LENS MATERIAL | MENICON CO., LTD. (JP) | 2006-08-30 | — | — | EP | disclosed |
| EP-0770888-B1 | Low water-absorptive ocular lens material, low water-absorptive ocular lens shaped product made thereof, low water-absorptive ocular lens made thereof and process for its production | MENICON CO LTD (JP) | 2004-08-04 | — | — | EP | disclosed |
| EP-0843184-B1 | Ocular lens material | MENICON CO LTD (JP) | 2004-03-03 | — | — | EP | disclosed |
| EP-0913713-B1 | Crosslinkable compound and an optical material employing it | MENICON CO LTD (JP) | 2002-12-18 | — | — | EP | disclosed |
| EP-0762149-B1 | Water-absorptive soft ocular lens material, water-absorptive soft ocular lens shaped product made thereof, water-absorptive soft ocular lens made thereof and process for its production | MENICON CO LTD (JP) | 2002-12-18 | — | — | EP | disclosed |
| EP-0854369-B1 | Ocular lens material | MENICON CO LTD (JP) | 2002-12-04 | — | — | EP | disclosed |
| EP-0794440-B1 | Ocular lens and a method for its production | MENICON CO LTD (JP) | 2001-05-23 | — | — | EP | disclosed |
| US-5817726-A | COPOLYMERIZING AN UNSATURATED METHOXYSILANE, CROSSLINKING WITH WATER | MENICON CO., LTD. (JP) | 1998-10-06 | — | — | US | disclosed |
| US-5811502-A | CONTAINING COPOLYMERS OF METHACRYLIC ESTERS AND HAVING OXYGEN PERMEABILITY, SUFFICIENT HARDNESS AND WETTABILITY | MENICON CO., LTD. (JP) | 1998-09-22 | — | — | US | disclosed |
| EP-0854369-A2 | Ocular lens material | Menicon Co., Ltd. (JP) | 1998-07-22 | — | — | EP | disclosed |
| US-5777032-A | ACRYLATE POLYMER AND SILICONE POLYMER | MENICON CO., LTD. (JP) | 1998-07-07 | — | — | US | disclosed |
| EP-0843184-A2 | Ocular lens material | Menicon Co., Ltd. (JP) | 1998-05-20 | — | — | EP | disclosed |
| US-5670594-A | POLYDIMETHYLSILOXANE POLYMERS WITH VINYL OR ACRYLATE GROUPS FOR INTRAOCULAR LENSES | MENICON CO., LTD. (JP) | 1997-09-23 | — | — | US | disclosed |
| EP-0794440-A2 | Ocular lens and a method for its production | Menicon Co., Ltd. (JP) | 1997-09-10 | — | — | EP | disclosed |
| EP-0781777-A1 | Silicon-containing compound and ocular lens material | Menicon Co., Ltd. (JP) | 1997-07-02 | — | — | EP | disclosed |
| EP-0770888-A2 | Low water-absorptive ocular lens material, low water-absorptive ocular lens shaped product made thereof, low water-absorptive ocular lens made thereof and process for its production | Menicon Co., Ltd. (JP) | 1997-05-02 | — | — | EP | disclosed |
| EP-0762149-A2 | Water-absorptive soft ocular lens material, water-absorptive soft ocular lens shaped product made thereof, water-absorptive soft ocular lens made thereof and process for its production | Menicon Co., Ltd. (JP) | 1997-03-12 | — | — | EP | disclosed |