Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 1.00 |
| ▸ | HTR2C | P28335 | 11/20 | 0.96 |
| ▸ | QDPR | P09417 | 2/20 | 0.64 |
| ▸ | HTR6 | P50406 | 3/20 | 0.60 |
| ▸ | HTR2A | P28223 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | HTR7 | P34969 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | RAD52 | P43351 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL446973 | 0.98 | HTR2C (1.00) | SIGMAR1HTR2CQDPRHTR6HTR2A | |
| Bromide SCHEMBL11385943 | 0.98 | SIGMAR1 (0.96) | SIGMAR1HTR2CQDPRHTR6HTR2A | |
| Hydrochloric Acid SCHEMBL3676212 | 0.96 | SIGMAR1 (0.92) | SIGMAR1HTR2CQDPRHTR6HTR2A | |
| SCHEMBL3899585 | 0.96 | SIGMAR1 (0.92) | SIGMAR1HTR2CQDPRHTR6HTR2A | |
| Acetonitrile SCHEMBL8683916 | 0.89 | SIGMAR1 (0.79) | SIGMAR1HTR2CQDPRHTR6HTR2A | |
| SCHEMBL4791120 | 0.89 | SIGMAR1 (0.79) | SIGMAR1HTR2CQDPRHTR6HTR2A | |
| Hydrochloric Acid SCHEMBL4793458 | 0.87 | HTR2C (0.79) | SIGMAR1HTR2CQDPRHTR6HTR2A | |
| SCHEMBL1954669 | 0.87 | SIGMAR1 (0.77) | SIGMAR1HTR2CQDPRHTR6HTR2A | |
| Hydrochloric Acid SCHEMBL6795900 | 0.85 | HTR2C (0.78) | SIGMAR1HTR2CQDPRHTR6HTR2A | |
| SCHEMBL7838514 | 0.83 | SIGMAR1 (0.70) | SIGMAR1HTR2CQDPRHTR6HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 696 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117820255-A | Application of catalyst and degradation method of ester substance | 上海科技大学 | 2024-04-05 | — | — | CN | claimed |
| WO-2020210428-A1 | NOVEL INHIBITORS OF FLAVIVIRUS PROTEASE FOR PREVENTION AND TREATMENT OF ZIKA, DENGUE AND OTHER FLAVIVIRUS INFECTIONS | BAYLOR COLLEGE OF MEDICINE (US) | 2020-10-15 | — | — | WO | claimed |
| EP-2983473-A2 | PHARMACEUTICAL COMPOSITION COMPRISING AN AMPK ACTIVATOR AND A SEROTONERGIC AGENT AND METHODS OF USE THEREOF | ALS Mountain Llc (US) | 2016-02-17 | — | — | EP | claimed |
| WO-2014144130-A2 | PHARMACEUTICAL COMPOSITION COMPRISING AN AMPK ACTIVATOR AND A SEROTONERGIC AGENT AND METHODS OF USE THEREOF | ALS MOUNTAIN LLC (US) | 2014-09-18 | — | — | WO | claimed |
| EP-1568770-A2 | Pharmaceutical use of compounds which bind to a mammalian \"trace amine\" receptor | Oregon Health & Science University (US) | 2005-08-31 | — | — | EP | claimed |
| US-20040072187-A1 | Novel mammalian receptor genes and uses | OREGON HEALTH & SCIENCE UNIVERSITY | 2004-04-15 | — | — | US | claimed |
| EP-1319070-A2 | MAMMALIAN RECEPTOR GENES AND USES | Oregon Health & Science University (US) | 2003-06-18 | — | — | EP | claimed |
| US-6514993-B1 | Useful in the treatment of certain psychic and neurologic disorders | H. LUNDBECK A/S (DK) | 2003-02-04 | — | — | US | claimed |
| EP-0703916-B1 | 14-SUBSTITUTED MARCFORTINES AND DERIVATIVES USEFUL AS ANTIPARASITIC AGENTS | UPJOHN CO (US) | 2002-08-14 | — | — | EP | claimed |
| WO-2002022801-A2 | MAMMALIAN RECEPTOR GENES AND USES | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2002-03-21 | — | — | WO | claimed |
| US-4593102-A | N-[(amino)alkyl]-1-pyrrolidine, 1-piperidine and 1-homopiperidinecarboxamides (and thiocarboxamides) with sulfur linked substitution in the 2, 3 or 4-position | A. H. ROBINS COMPANY, INC. (US) | 1986-06-03 | — | — | US | claimed |
| US-4558155-A | N-(Aryloxyalkyl)-N'-(aminoalkyl)thioureas | A. H. ROBINS COMPANY, INCORPORATED (US) | 1985-12-10 | — | — | US | claimed |
| EP-0160436-A2 | N-[(Amino)Alkyl]-1-pyrrolidine, 1-piperidine and 1-homopiperidinecarboxamides (and thiocarboxamides) with sulphur linked substitution in the 2, 3 or 4-position | A.H. ROBINS COMPANY, INCORPORATED (US) | 1985-11-06 | — | — | EP | claimed |
| US-4546177-A | 1-(6-Hydroxy-4- or -7-methoxy-5-Benzofuranyl)-4-substituted-1,3-butanediones | THE UPJOHN COMPANY (US) | 1985-10-08 | — | — | US | claimed |
| US-4500529-A | ANTIARRHYTHMIA AGENT | A. H. ROBINS COMPANY, INCORPORATED (US) | 1985-02-19 | — | — | US | claimed |
| US-4487774-A | Isochromans | THE UPJOHN COMPANY (US) | 1984-12-11 | — | — | US | claimed |
| US-4434295-A | Anti-atherosclerotic 6,7-dihydro-7,7-disubstituted-khellin analogs | THE UPJOHN COMPANY (US) | 1984-02-28 | — | — | US | claimed |
| EP-0059989-A1 | 2,3- and 3,4-dehydro-5-phenylmorphans and their preparation | ELI LILLY AND COMPANY (US) | 1982-09-15 | — | — | EP | claimed |
| US-4236009-A | Method of preparing 4A-arylhexahydro-1H-2-pyrindines and 4A-aryloctahydroisoquinolines | ELI LILLY AND COMPANY (US) | 1980-11-25 | — | — | US | claimed |
| EP-0018077-A2 | Phenylmorphans, processes for their preparation and pharmaceutical compositions containing them | ELI LILLY AND COMPANY (US) | 1980-10-29 | — | — | EP | claimed |