Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C known ✓ | P28335 | 11/20 | 1.00 |
| ▸ | SIGMAR1 known ✓ | Q99720 | 2/20 | 0.96 |
| ▸ | HTR6 known ✓ | P50406 | 3/20 | 0.58 |
| ▸ | HTR2A known ✓ | P28223 | 2/20 | 0.58 |
| ▸ | DRD2 known ✓ | P14416 | 1/20 | 0.54 |
| ▸ | HTR7 known ✓ | P34969 | 1/20 | 0.50 |
| ▸ | GAA known ✓ | P10253 | 1/20 | 0.47 |
| ▸ | QDPR | P09417 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | RAD52 | P43351 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL415545 | 0.98 | SIGMAR1 (1.00) | HTR2CSIGMAR1QDPRHTR6HTR2A | |
| Bromide SCHEMBL11385943 | 0.96 | SIGMAR1 (0.96) | HTR2CSIGMAR1QDPRHTR6HTR2A | |
| Hydrochloric Acid SCHEMBL3676212 | 0.94 | SIGMAR1 (0.92) | HTR2CSIGMAR1QDPRHTR6HTR2A | |
| SCHEMBL3899585 | 0.94 | SIGMAR1 (0.92) | HTR2CSIGMAR1QDPRHTR6HTR2A | |
| Hydrochloric Acid SCHEMBL4793458 | 0.89 | HTR2C (0.79) | HTR2CSIGMAR1QDPRHTR6HTR2A | |
| Hydrochloric Acid SCHEMBL6795900 | 0.88 | HTR2C (0.78) | HTR2CSIGMAR1QDPRHTR6HTR2A | |
| SCHEMBL4791120 | 0.87 | SIGMAR1 (0.79) | HTR2CSIGMAR1QDPRHTR6HTR2A | |
| Acetonitrile SCHEMBL8683916 | 0.87 | SIGMAR1 (0.79) | HTR2CSIGMAR1QDPRHTR6HTR2A | |
| SCHEMBL1954669 | 0.85 | SIGMAR1 (0.77) | HTR2CSIGMAR1QDPRHTR6HTR2A | |
| SCHEMBL7838514 | 0.81 | SIGMAR1 (0.70) | HTR2CSIGMAR1QDPRHTR6HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 590 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3541913-B1 | FABRIC TREATMENT COMPOSITIONS AND METHODS FOR PROVIDING A BENEFIT | PROCTER & GAMBLE (US) | 2026-04-22 | — | — | EP | claimed |
| US-20250295826-A1 | FRAGRANCES AS UREASE INHIBITORS | SYMRISE AG (DE) | 2025-09-25 | — | — | US | claimed |
| US-20250235136-A1 | ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2025-07-24 | — | — | US | claimed |
| US-20250163343-A1 | FRAGRANCE COMPOSITIONS FOR SLEEP IMPROVEMENT | INTERNATIONAL FLAVORES & FRAGRANCES INC. | 2025-05-22 | — | — | US | claimed |
| EP-4486857-A1 | FRAGRANCE COMPOSITIONS FOR SLEEP IMPROVEMENT | International Flavors & Fragrances Inc. (US) | 2025-01-08 | — | — | EP | claimed |
| CN-118922068-A | Perfume as urease inhibitor | 西姆莱斯股份公司 | 2024-11-08 | — | — | CN | claimed |
| US-20240306688-A1 | METHOD OF MITIGATING OFF-ODORS | GIVAUDAN SA (CH) | 2024-09-19 | — | — | US | claimed |
| US-20240206778-A1 | FRAGRANCE FOR IMPROVING INVIGORATION STATE AND METHOD OF ASSESSING | GIVAUDAN SA (CH) | 2024-06-27 | — | — | US | claimed |
| US-12016943-B2 | Antiperspirant or deodorant composition | FIRMENICH SA (CH) | 2024-06-25 | — | — | US | claimed |
| US-20240197221-A1 | FRAGRANCE FOR IMPROVING HAPPINESS STATE AND METHOD OF ASSESSING | GIVAUDAN SA (CH) | 2024-06-20 | — | — | US | claimed |
| EP-4347758-A1 | FRAGRANCE FOR IMPROVING HAPPINESS STATE AND METHOD OF ASSESSING | Givaudan SA (CH) | 2024-04-10 | — | — | EP | claimed |
| EP-4319715-A1 | FRAGRANCE COMPOSITION | Givaudan SA (CH) | 2024-02-14 | — | — | EP | claimed |
| WO-2023168069-A1 | FRAGRANCE COMPOSITIONS FOR SLEEP IMPROVEMENT | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2023-09-07 | — | — | WO | claimed |
| US-20220364016-A1 | PERFUME OIL MIXTURE | SYMRISE AG (DE) | 2022-11-17 | — | — | US | claimed |
| WO-2022234150-A1 | FRAGRANCE FOR IMPROVING HAPPINESS STATE AND METHOD OF ASSESSING | GIVAUDAN SA (CH) | 2022-11-10 | — | — | WO | claimed |
| WO-2022234151-A1 | FRAGRANCE FOR IMPROVING INVIGORATION STATE AND METHOD OF ASSESSING | GIVAUDAN SA (CH) | 2022-11-10 | — | — | WO | claimed |
| US-20220334094-A1 | IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2022-10-20 | — | — | US | claimed |
| WO-2022214636-A1 | FRAGRANCE COMPOSITION | GIVAUDAN SA (CH) | 2022-10-13 | — | — | WO | claimed |
| EP-4025675-A1 | A PERFUME OIL MIXTURE | Symrise AG (DE) | 2022-07-13 | — | — | EP | claimed |
| EP-3990596-A2 | IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS | Givaudan SA (CH) | 2022-05-04 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12016943-B2 | Antiperspirant or deodorant composition | LPO, SIGMAR1, DEK | HTR2C 2205/4885SIGMAR1 2/4885HTR6 2586/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.