SCHEMBL4155468

SCHEMBL4155468

C=CCOc1nc(OCC2CO2)nc(OCC2CO2)n1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.53
MAPT P10636 3/20 0.44
MAPK1 P28482 1/20 0.44
TDP1 Q9NUW8 1/20 0.38
TSHR P16473 4/20 0.37
TP53 P04637 3/20 0.37
HIF1A Q16665 2/20 0.37
CYP3A4 P08684 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
GLA P06280 1/20 0.35
GPR84 Q9NQS5 3/20 0.33
HPGD P15428 2/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
CYP1A2 P05177 1/20 0.33
PPARG P37231 1/20 0.33
LMNA P02545 1/20 0.33
GAA P10253 1/20 0.33
PKM P14618 1/20 0.33
FGFR1 P11362 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11190248 1.00 ALDH1A1 (0.53) ALDH1A1MAPTMAPK1TDP1TSHR
SCHEMBL11207182 0.94 ALDH1A1 (0.47) ALDH1A1MAPTMAPK1TDP1TSHR
SCHEMBL29398866 0.84 TDP1 (0.48) ALDH1A1MAPTMAPK1TDP1TSHR
SCHEMBL29397562 0.84 TDP1 (0.48) ALDH1A1MAPTMAPK1TDP1TSHR
SCHEMBL487480 0.84 TDP1 (0.48) ALDH1A1MAPTMAPK1TDP1TSHR
SCHEMBL21756589 0.81 ALDH1A1 (0.49) ALDH1A1MAPTMAPK1TDP1
SCHEMBL20228536 0.79 ALDH1A1 (0.39) ALDH1A1TDP1TSHRTP53HIF1A
SCHEMBL23181 0.78 MAPK1 (0.55) ALDH1A1MAPTMAPK1TSHRHPGD
SCHEMBL12747113 0.78 TDP1 (0.40) ALDH1A1MAPTMAPK1TDP1TSHR
SCHEMBL3677603 0.77 TDP1 (0.42) ALDH1A1MAPTMAPK1TDP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090197083-A1 HEAT-RESISTANT RESIN COMPOSITION AND INSULATED WIRE INSULATED THEREWITH HITACHI METALS, LTD. (JP) 2009-08-06 US claimed
US-7541544-B2 Polyester resin composition and insulated wire using same HITACHI CABLE, LTD. (JP) 2009-06-02 US claimed
US-20080193756-A1 POLYESTER RESIN COMPOSITION AND INSULATED WIRE USING SAME HITACHI CABLE, LTD. (JP) 2008-08-14 US claimed
EP-0019113-B1 AROMATIC POLYAMIDE PAPER-LIKE SHEET AND PROCESSES FOR PRODUCING THE SAME TEIJIN LIMITED (JP) 1983-04-13 EP claimed
US-4369207-A PHOTOPOLYMERIZING TEIJIN LIMITED (JP) 1983-01-18 US claimed
US-20200181317-A1 Bisphenol A-Free Crosslinked Polymer Composition WARNER BABCOCK INSTITUTE FOR GREEN CHEMISTRY, LLC (US) 2020-06-11 US disclosed
US-10454008-B2 Resin composition, reflector, lead frame with reflector, and semiconductor light-emitting device DAI NIPPON PRINTING CO., LTD. (JP) 2019-10-22 US disclosed
CN-105916931-B Resin combination, reflector, lead frame and semiconductor light-emitting apparatus with reflector 大日本印刷株式会社 2019-07-12 CN disclosed
US-20160372645-A1 RESIN COMPOSITION, REFLECTOR, LEAD FRAME WITH REFLECTOR, AND SEMICONDUCTOR LIGHT-EMITTING DEVICE DAI NIPPON PRINTING CO., LTD. (JP) 2016-12-22 US disclosed
CN-105916931-A Resin composition, reflector, lead frame with reflector, and semiconductor light-emitting device 大日本印刷株式会社 2016-08-31 CN disclosed
CN-103122140-B Resin composition and molded article comprising the same UNITIKA LTD 2015-07-22 CN disclosed
US-8257910-B1 Underlayers for EUV lithography BREWER SCIENCE INC. (US) 2012-09-04 US disclosed
US-7541544-B2 Polyester resin composition and insulated wire using same HITACHI CABLE, LTD. (JP) 2009-06-02 US disclosed
US-20090004472-A1 INSULATED CONDUCTOR AND METHOD FOR MANUFACTURING SAME HITACHI CABLE, LTD. (JP) 2009-01-01 US disclosed
US-20080193756-A1 POLYESTER RESIN COMPOSITION AND INSULATED WIRE USING SAME HITACHI CABLE, LTD. (JP) 2008-08-14 US disclosed
US-4498957-A Aromatic polyamide paper-like sheet and processes for producing the same TEIJIN LIMITED (JP) 1985-02-12 US disclosed
EP-0019113-B1 AROMATIC POLYAMIDE PAPER-LIKE SHEET AND PROCESSES FOR PRODUCING THE SAME TEIJIN LIMITED (JP) 1983-04-13 EP disclosed
US-4369207-A PHOTOPOLYMERIZING TEIJIN LIMITED (JP) 1983-01-18 US disclosed
EP-0019113-A1 Aromatic polyamide paper-like sheet and processes for producing the same TEIJIN LIMITED (JP) 1980-11-26 EP disclosed
EP-0015441-A2 Laminated film structure of aromatic polyester and process for production thereof TEIJIN LIMITED (JP) 1980-09-17 EP disclosed