Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 1/20 | 0.68 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.49 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.48 |
| ▸ | KIF11 | P52732 | 1/20 | 0.47 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.47 |
| ▸ | SELE | P16581 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.45 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30775024 | 1.00 | CTNNB1 (0.68) | CTNNB1PARP10SCN9AKIF11ICAM1 | |
| SCHEMBL9138387 | 0.86 | CTNNB1 (0.51) | CTNNB1SCN9ARXFP1KDM4EMAPK14 | |
| SCHEMBL4155251 | 0.84 | CTNNB1 (0.68) | CTNNB1PARP10SMN1; SMN2IRAK4MAPT | |
| SCHEMBL15901648 | 0.84 | CTNNB1 (0.62) | CTNNB1PARP10SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL30775020 | 0.84 | CTNNB1 (0.62) | CTNNB1SCN9AICAM1SELERXFP1 | |
| SCHEMBL27800575 | 0.83 | CTNNB1 (0.77) | CTNNB1PARP10SCN9ASMN1; SMN2IRAK4 | |
| Trifluoroacetic Acid SCHEMBL5478809 | 0.83 | CTNNB1 (0.81) | CTNNB1PARP10SMN1; SMN2RXFP1IRAK4 | |
| SCHEMBL28751454 | 0.82 | CTNNB1 (0.59) | CTNNB1SCN9ASMN1; SMN2RXFP1KDM4E | |
| SCHEMBL5724 | 0.81 | CTNNB1 (1.00) | CTNNB1PARP10SMN1; SMN2IRAK4SIRT2 | |
| SCHEMBL28876495 | 0.81 | CTNNB1 (1.00) | CTNNB1PARP10SMN1; SMN2IRAK4SIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1960347-B1 | 17-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 3 (17BETA-HSD3) INHIBITORS | STERIX LTD (GB) | 2012-06-20 | — | — | EP | disclosed |
| US-20090023710-A1 | Compound | OXFORD UNIVERSITY INNOVATION LIMITED (GB) | 2009-01-22 | — | — | US | disclosed |
| EP-1960347-A2 | 17-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 3 (17BETA-HSD3) INHIBITORS | Sterix Limited (GB) | 2008-08-27 | — | — | EP | disclosed |
| WO-2007003934-A2 | 17BETA-HYDR0XYSTER0ID DEHYDROGENASE TYPE 3 (17BETA-HSD3 ) INHIBITORS | STERIX LIMITED (GB) | 2007-01-11 | — | — | WO | disclosed |
| CN-1245368-C | (4-(4'-trifluoromethyl)phenoxy phenyl)-hydroquinone and its synthesis method and application in polymer material | UNIV JILIN (CN) | 2006-03-15 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090023710-A1 | Compound | NR1H3, NR1H2, NR1H4 | CTNNB1 2627/4885PARP10 2575/4885SCN9A 1009/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.