SCHEMBL415619

SCHEMBL415619

CCC(=O)NOC(=O)Nc1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.57
MAPT P10636 3/20 0.57
ALDH1A1 P00352 5/20 0.54
SMN1; SMN2 Q16637 3/20 0.54
RAB9A P51151 5/20 0.50
HPGD P15428 3/20 0.50
NPC1 O15118 2/20 0.48
KMT2A Q03164 2/20 0.47
L3MBTL1 Q9Y468 2/20 0.46
CRHBP P24387 1/20 0.46
CRHR2 Q13324 1/20 0.46
HTT P42858 1/20 0.46
HSD17B10 Q99714 2/20 0.46
NAPRT Q6XQN6 1/20 0.46
LMNA P02545 1/20 0.45
MAPK1 P28482 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11676832 0.82 SOAT2 (0.60) ALDH1A1HTT
SCHEMBL9707304 0.80 NAPRT (0.61) GAAMAPTALDH1A1SMN1; SMN2RAB9A
SCHEMBL9706 0.79 MAPT (0.85) GAAMAPTALDH1A1SMN1; SMN2RAB9A
SCHEMBL25522587 0.79 RAB9A (0.53) GAAMAPTALDH1A1SMN1; SMN2RAB9A
SCHEMBL25525421 0.78 RAB9A (0.49) GAAMAPTALDH1A1SMN1; SMN2RAB9A
SCHEMBL11340463 0.77 GAA (0.81) GAAMAPTALDH1A1SMN1; SMN2RAB9A
SCHEMBL11341322 0.77 GAA (0.81) GAAMAPTALDH1A1SMN1; SMN2RAB9A
Hydrochloric Acid SCHEMBL29096649 0.77 GAA (0.81) GAAMAPTALDH1A1SMN1; SMN2RAB9A
SCHEMBL27806510 0.77 GAA (0.81) GAAMAPTALDH1A1SMN1; SMN2RAB9A
SCHEMBL11334339 0.77 GAA (0.81) GAAMAPTALDH1A1SMN1; SMN2RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250277230-A1 PARTHENOGENESIS METHODS AND COMPOSITIONS PIONEER HI-BRED INTERNATONAL, INC. (US) 2025-09-04 US disclosed
US-20240002877-A1 PARTHENOGENESIS FACTORS AND METHODS OF USING SAME PIONEER HI-BRED INTERNATIONAL, INC. (US) 2024-01-04 US disclosed
US-9121032-B2 Selective ablation of diploid embryos E I DU PONT DE NEMOURS AND COMPANY (US) 2015-09-01 US disclosed
US-8859846-B2 Doubling of chromosomes in haploid embryos E. I. DU PONT DE NEMOURS AND COMPANY (US) 2014-10-14 US disclosed
US-20120311736-A1 SELECTIVE ABLATION OF DIPLOID EMBRYOS E.I. du Pont de Nemours and Company and Pioneer Hi-Bred International 2012-12-06 US disclosed
US-8269061-B2 Selective ablation of diploid embryos E.I. du Pont de Nmeours and Company (US) 2012-09-18 US disclosed
US-20120023612-A1 SELECTIVE ABLATION OF DIPLOID EMBRYOS E. I. DU PONT DE NEMOURS AND COMPANY AND PIONEER HI-BRED INTERNATIONAL, INC. (US) 2012-01-26 US disclosed
US-20080216191-A1 Pollinating silks of maize ear, contacting haploid embryo with chromosome doubling agent (colchicine), propagate cells; generating homozygosity in plants PIONEER HI-BRED INTERNATIONAL, INC. (US) 2008-09-04 US disclosed
US-5688745-A Arylsulfonylureas and their use as herbicides and growth regulators HOECHST AKTIENGESELLSCHAFT (DE) 1997-11-18 US disclosed