Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL415871 | 0.97 | ADRB2 (0.41) | ADRB2ADRB1ADRB3TSHRCYP3A4 | |
| SCHEMBL11118509 | 0.92 | THRB (0.35) | TSHRCA1CA2THRB | |
| SCHEMBL8837549 | 0.91 | ADRB2 (0.39) | ADRB2ADRB1ADRB3TSHRCYP3A4 | |
| SCHEMBL49555 | 0.85 | ADRB2 (0.45) | ADRB2ADRB1ADRB3TSHRCYP3A4 | |
| SCHEMBL4455209 | 0.84 | ADRB2 (0.42) | ADRB2ADRB1ADRB3TSHRCYP3A4 | |
| SCHEMBL2761917 | 0.84 | ADRB2 (0.36) | ADRB2ADRB1ADRB3TSHRCYP3A4 | |
| SCHEMBL10624029 | 0.82 | — | — | |
| SCHEMBL29053698 | 0.82 | ADRB2 (0.43) | ADRB2ADRB1ADRB3TSHRCYP3A4 | |
| SCHEMBL11408215 | 0.80 | ADRB2 (0.33) | ADRB2ADRB1ADRB3TSHRCYP3A4 | |
| SCHEMBL17644807 | 0.80 | ADRB2 (0.41) | ADRB2ADRB1ADRB3TSHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 120 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12590185-B2 | Rapid-curing two-component silicone composition having a longer mixer open time | SIKA TECHNOLOGY AG (CH) | 2026-03-31 | — | — | US | disclosed |
| EP-4711411-A1 | FAST-CURING TWO-COMPONENT SILICONE COMPOSITION WITH IMPROVED TEMPERATURE STABILITY | Sika Technology AG (CH) | 2026-03-18 | — | — | EP | disclosed |
| EP-4255986-B1 | RAPID CURING TWO-COMPONENT SILICONE COMPOSITION WITH LONG-TERM MIXER OPEN TIME | SIKA TECH AG (CH) | 2024-11-20 | — | — | EP | disclosed |
| CN-116507668-B | Additive stabilization | 美国陶氏有机硅公司 | 2024-05-31 | — | — | CN | disclosed |
| US-20240166850-A1 | RAPID-CURING TWO-COMPONENT COMPOSITION OF SILYLATED POLYMERS HAVING A LONG OPEN TIME | SIKA TECHNOLOGY AG (CH) | 2024-05-23 | — | — | US | disclosed |
| EP-4326794-A1 | RAPID-CURING TWO-COMPONENT COMPOSITION OF SILYLATED POLYMERS HAVING A LONG OPEN TIME | Sika Technology AG (CH) | 2024-02-28 | — | — | EP | disclosed |
| CN-115038756-B | Fast curing two-component silicone composition with adjustable pot life | SIKA技术股份公司 | 2024-02-27 | — | — | CN | disclosed |
| EP-3635063-B1 | FIRE-RESISTANT COMPOUND, MULTICOMPONENT SYSTEM AND ITS UTILISATION | HILTI AG (LI) | 2023-12-13 | — | — | EP | disclosed |
| CN-117178004-A | Two-component composition of rapidly curing silylated polymers with long open times | SIKA技术股份公司 | 2023-12-05 | — | — | CN | disclosed |
| US-20230365763-A1 | ADDITIVE STABILIZATION | DOW SILICONES CORPORATION | 2023-11-16 | — | — | US | disclosed |
| EP-2358819-A1 | STORAGE-STABLE TWO-COMPONENT SILICONE ADHESIVES AND SEALANTS WITH EXTENDED MIXER OPEN TIME | Sika Technology AG (CH) | 2011-08-24 | — | — | EP | disclosed |
| EP-2202276-A1 | Silicon compound with accelerated integration | Sika Technology AG (CH) | 2010-06-30 | — | — | EP | disclosed |
| WO-2010057963-A1 | STORAGE-STABLE TWO-COMPONENT SILICONE ADHESIVES AND SEALANTS WITH EXTENDED MIXER OPEN TIME | SIKA TECHNOLOGY AG (CH) | 2010-05-27 | — | — | WO | disclosed |
| EP-2189501-A1 | Storage-stable two-component silicone adhesives and sealants having a prolonged open time in a mixer | Sika Technology AG (CH) | 2010-05-26 | — | — | EP | disclosed |
| US-20060247349-A1 | Process for producing flowable, crosslinkable polyorganosiloxane compositions comprising reinforcing filler | WACKER CHEMIE AG (DE) | 2006-11-02 | — | — | US | disclosed |
| EP-1717268-A1 | Process for the preparation of flowable, curable polyorganosiloxane masses containing reinforcing filler | Wacker Chemie AG (DE) | 2006-11-02 | — | — | EP | disclosed |
| EP-0787766-B2 | Ambient vulcanising silicone rubbers crosslinking by condensation mechanism | WACKER CHEMIE GMBH (DE) | 2004-03-17 | — | — | EP | disclosed |
| US-6172150-B1 | CONDENSATION-CROSSLINKING, ROOM-TEMPERATURE VULCANIZING SILICONE RUBBER HAVIN IMPROVED SERVICE LILFE WHEN USED AS FEMALE MOLD CONTAINS A MOLD-LIFE EXTENDING COMPONENT COMPRISING ONE OR MORE DIORGANO DITHIOPHOSPHATES | WACKER-CHEMIE GMBH (DE) | 2001-01-09 | — | — | US | disclosed |
| EP-0787766-B1 | Ambient vulcanising silicone rubbers crosslinking by condensation mechanism | WACKER CHEMIE GMBH (DE) | 1999-08-04 | — | — | EP | disclosed |
| EP-0787766-A1 | Ambient vulcanising silicone rubbers crosslinking by condensation mechanism | Wacker-Chemie GmbH (DE) | 1997-08-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12590185-B2 | Rapid-curing two-component silicone composition having a longer mixer open time | MSR1, VCL, ASH2L | ADRB2 2927/4885ADRB1 3803/4885ADRB3 4358/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.