SCHEMBL415656

SCHEMBL415656

Cc1cc(C)c2c(c1)CC(C)C2

nearest known ligand 0.37

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 3/20 0.37
DRD1 P21728 3/20 0.37
UGT2B17 O75795 2/20 0.36
ALDH1A1 P00352 1/20 0.32
MAPT P10636 1/20 0.32
HTT P42858 1/20 0.32
BRD4 O60885 1/20 0.32
CREBBP Q92793 1/20 0.32
RAPGEF4 Q8WZA2 1/20 0.31
HTR2A P28223 1/20 0.30
HTR2C P28335 1/20 0.30
HTR2B P41595 1/20 0.30
CRBN Q96SW2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29511500 1.00 DRD2 (0.37) DRD2DRD1UGT2B17ALDH1A1MAPT
SCHEMBL5611547 0.79 KDM4E (0.31) ALDH1A1HTR2AHTR2CHTR2B
SCHEMBL21386525 0.79 NOTUM (0.32) BRD4CREBBP
SCHEMBL20368612 0.79 ALDH1A1 (0.33) ALDH1A1MAPT
SCHEMBL8689227 0.77 FYN (0.40) DRD2DRD1UGT2B17ALDH1A1MAPT
SCHEMBL29605226 0.77 FYN (0.40) DRD2DRD1UGT2B17ALDH1A1MAPT
SCHEMBL18466748 0.77 DRD2 (0.36) DRD2DRD1UGT2B17ALDH1A1MAPT
SCHEMBL25961964 0.77 DRD2 (0.36) DRD2DRD1UGT2B17ALDH1A1MAPT
Hydrochloric Acid SCHEMBL10446675 0.75 FYN (0.39) DRD2DRD1UGT2B17ALDH1A1MAPT
SCHEMBL21231560 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8895789-B2 Fuel composition for use in gasoline engines SHELL OIL COMPANY (US) 2014-11-25 US claimed
US-8895789-B2 Fuel composition for use in gasoline engines SHELL OIL COMPANY (US) 2014-11-25 US disclosed
US-8876920-B2 Fuel composition for use in gasoline engines SHELL OIL COMPANY (US) 2014-11-04 US disclosed
EP-2367907-B1 FUEL COMPOSITION FOR USE IN GASOLINE ENGINES SHELL INT RESEARCH (NL) 2013-04-24 EP disclosed
EP-2367908-B1 FUEL COMPOSITION FOR USE IN GASOLINE ENGINES SHELL INT RESEARCH (NL) 2013-02-20 EP disclosed
US-20120101316-A1 METHOD FOR THE PREPARATION OF A FUEL COMPOSITION FOR USE IN GASOLINE ENGINES AND BLENDING COMPONENT SHELL OIL COMPANY 2012-04-26 US disclosed
US-20120022304-A1 FUEL COMPOSITION FOR USE IN GASOLINE ENGINES SHELL OIL COMPANY (US) 2012-01-26 US disclosed
EP-2367908-A1 FUEL COMPOSITION FOR USE IN GASOLINE ENGINES Shell Internationale Research Maatschappij B.V. (NL) 2011-09-28 EP disclosed
EP-2367906-A1 METHOD FOR THE PREPARATION OF A FUEL COMPOSITION FOR USE IN GASOLINE ENGINES AND BLENDING COMPONENT Shell Internationale Research Maatschappij B.V. (NL) 2011-09-28 EP disclosed
EP-2367907-A1 FUEL COMPOSITION FOR USE IN GASOLINE ENGINES Shell Internationale Research Maatschappij B.V. (NL) 2011-09-28 EP disclosed
WO-2010066876-A1 FUEL COMPOSITION FOR USE IN GASOLINE ENGINES SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) 2010-06-17 WO disclosed
WO-2010066881-A1 METHOD FOR THE PREPARATION OF A FUEL COMPOSITION FOR USE IN GASOLINE ENGINES AND BLENDING COMPONENT SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) 2010-06-17 WO disclosed
WO-2010066879-A1 FUEL COMPOSITION FOR USE IN GASOLINE ENGINES SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) 2010-06-17 WO disclosed