Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | TPH1 | P17752 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | FCER2 | P06734 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | PADI1 | Q9ULC6 | 3/20 | 0.34 |
| ▸ | PADI4 | Q9UM07 | 3/20 | 0.34 |
| ▸ | PADI2 | Q9Y2J8 | 2/20 | 0.34 |
| ▸ | PADI3 | Q9ULW8 | 2/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4151722 | 0.97 | SIRT2 (0.41) | SIRT2HDAC1HDAC2CES1MCHR1 | |
| Trifluoroacetic Acid SCHEMBL4166172 | 0.88 | SIRT2 (0.41) | SIRT2HDAC1HDAC2CES1MCHR1 | |
| Trifluoroacetic Acid SCHEMBL4166154 | 0.87 | SIRT2 (0.38) | SIRT2HDAC1HDAC2CES1MCHR1 | |
| Trifluoroacetic Acid SCHEMBL4165163 | 0.85 | SIRT2 (0.38) | SIRT2HDAC1HDAC2CES1MCHR1 | |
| Trifluoroacetic Acid SCHEMBL4162623 | 0.84 | SIRT2 (0.38) | SIRT2HDAC1HDAC2CES1MCHR1 | |
| Trifluoroacetic Acid SCHEMBL4149911 | 0.83 | SIRT2 (0.35) | SIRT2HDAC1HDAC2CES1MCHR1 | |
| SCHEMBL4151724 | 0.81 | MCHR1 (0.41) | SIRT2HDAC1HDAC2CES1MCHR1 | |
| Trifluoroacetic Acid SCHEMBL4154033 | 0.79 | CYP1A2 (0.39) | SIRT2CYP1A2 | |
| Trifluoroacetic Acid SCHEMBL4163740 | 0.78 | MCHR1 (0.41) | HDAC1HDAC2CES1MCHR1FCER2 | |
| Trifluoroacetic Acid SCHEMBL4162613 | 0.77 | MCHR1 (0.35) | HDAC1HDAC2CES1MCHR1MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090054448-A1 | Amino Acid Derivatives as Histone Deacetylase (HDAC) Inhibitors | JONES PHILIP | 2009-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090054448-A1 | Amino Acid Derivatives as Histone Deacetylase (HDAC) Inhibitors | HDAC5, HDAC1, HDAC11 | SIRT2 127/4885HDAC1 2/4885HDAC2 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.