Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CDYL2 | Q8N8U2 | 2/20 | 0.36 |
| ▸ | CDYL | Q9Y232 | 2/20 | 0.36 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 2/20 | 0.36 |
| ▸ | CBX7 | O95931 | 1/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4166154 | 0.84 | SIRT2 (0.38) | SIRT2 | |
| SCHEMBL4151885 | 0.82 | KMT2A (0.43) | CYP1A2CYP2C19CYP3A4CYP2C9POLB | |
| Trifluoroacetic Acid SCHEMBL4166172 | 0.82 | SIRT2 (0.41) | SIRT2 | |
| Trifluoroacetic Acid SCHEMBL4165163 | 0.82 | SIRT2 (0.38) | SIRT2 | |
| Trifluoroacetic Acid SCHEMBL4162623 | 0.81 | SIRT2 (0.38) | CYP1A2SIRT2 | |
| Trifluoroacetic Acid SCHEMBL4156590 | 0.79 | SIRT2 (0.41) | CYP1A2SIRT2 | |
| Trifluoroacetic Acid SCHEMBL4171443 | 0.77 | CHRM1 (0.38) | CYP1A2CYP2C19CYP3A4CYP2C9POLB | |
| Trifluoroacetic Acid SCHEMBL4149911 | 0.77 | SIRT2 (0.35) | SIRT2 | |
| SCHEMBL4151722 | 0.77 | SIRT2 (0.41) | CYP1A2SIRT2 | |
| Trifluoroacetic Acid SCHEMBL4168647 | 0.75 | LMNA (0.35) | CYP1A2CYP2C19CYP3A4CYP2C9POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090054448-A1 | Amino Acid Derivatives as Histone Deacetylase (HDAC) Inhibitors | JONES PHILIP | 2009-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090054448-A1 | Amino Acid Derivatives as Histone Deacetylase (HDAC) Inhibitors | HDAC5, HDAC1, HDAC11 | CYP1A2 2863/4885CYP2C19 2603/4885CYP3A4 3542/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.