Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 2/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MIF | P14174 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2844548 | 0.97 | TAAR1 (0.44) | TAAR1AOC3ADRA2AADRA2CCYP2D6 | |
| SCHEMBL3886956 | 0.86 | AOC3 (0.45) | TAAR1AOC3ADRA2AADRA2CCYP2D6 | |
| SCHEMBL1130427 | 0.85 | LMNA (0.43) | TAAR1LMNAKDM4ETSHR | |
| SCHEMBL10734368 | 0.82 | LMNA (0.46) | AOC3ADRA2AADRA2CCYP2D6LMNA | |
| SCHEMBL908216 | 0.82 | TAAR1 (0.50) | TAAR1ADRA2AADRA2CCYP2D6LMNA | |
| SCHEMBL27948397 | 0.77 | CYP2D6 (0.46) | CYP2D6LMNA | |
| SCHEMBL30307009 | 0.77 | TRPA1 (0.43) | TAAR1AOC3ADRA2AADRA2CCYP2D6 | |
| SCHEMBL599878 | 0.77 | TAAR1 (0.48) | TAAR1AOC3ADRA2AADRA2CCYP2D6 | |
| SCHEMBL19519886 | 0.77 | TAAR1 (0.48) | TAAR1AOC3ADRA2AADRA2CCYP2D6 | |
| SCHEMBL825973 | 0.77 | AOC3 (0.50) | TAAR1AOC3ADRA2AADRA2CCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2009304-B1 | TORQUE LIMITER | JTEKT CORP (JP) | 2014-10-01 | — | — | EP | disclosed |
| EP-2003353-B1 | TORQUE LIMITER | JTEKT CORP (JP) | 2014-06-04 | — | — | EP | disclosed |
| US-8230986-B2 | Torque limiter | JTEKT CORPORATION (JP) | 2012-07-31 | — | — | US | disclosed |
| US-8220609-B2 | Torque limiter | JTEKT CORPORATION (JP) | 2012-07-17 | — | — | US | disclosed |
| US-20090173591-A1 | TORQUE LIMITER | JTEKT CORPORATION (JP) | 2009-07-09 | — | — | US | disclosed |
| EP-2009304-A1 | TORQUE LIMITER | JTEKT Corporation (JP) | 2008-12-31 | — | — | EP | disclosed |
| EP-2003353-A1 | TORQUE LIMITER | JTEKT Corporation (JP) | 2008-12-17 | — | — | EP | disclosed |