Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 6/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7567512 | 1.00 | TRPM8 (0.61) | TRPM8NPSR1ALDH1A1POLBNPC1 | |
| SCHEMBL30764040 | 0.83 | TRPM8 (0.66) | TRPM8NPSR1ALDH1A1POLBNPC1 | |
| SCHEMBL5175916 | 0.82 | LMNA (0.48) | TRPM8ALDH1A1POLBNPC1HTT | |
| SCHEMBL5176493 | 0.82 | LMNA (0.48) | TRPM8ALDH1A1POLBNPC1HTT | |
| SCHEMBL5175903 | 0.82 | LMNA (0.48) | TRPM8ALDH1A1POLBNPC1HTT | |
| SCHEMBL29078085 | 0.82 | TRPM8 (0.42) | TRPM8 | |
| SCHEMBL7456057 | 0.82 | TRPM8 (0.42) | TRPM8NPSR1ALDH1A1POLBTDP1 | |
| SCHEMBL14675119 | 0.81 | TRPM8 (0.41) | TRPM8ALDH1A1POLBNPC1HTT | |
| SCHEMBL15708932 | 0.79 | TRPM8 (0.45) | TRPM8ALDH1A1NPC1HTTRAB9A | |
| SCHEMBL14677361 | 0.79 | TRPM8 (0.45) | TRPM8ALDH1A1NPC1HTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090131657-A1 | PROCESS FOR ALKENYLATING CARBOXAMIDES | BASF SE (DE) | 2009-05-21 | — | — | US | disclosed |
| EP-0115218-B1 | POLYPHENYLENE ETHER COMPOSITIONS HAVING IMPROVED PROCESSABILITY | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1989-10-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090131657-A1 | PROCESS FOR ALKENYLATING CARBOXAMIDES | PRMT5, CYC1, CBR3 | TRPM8 2557/4885NPSR1 3299/4885ALDH1A1 1506/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.