Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 3/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | MLNR | O43193 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2458836 | 0.75 | SLC6A2 (0.40) | TSHRSMN1; SMN2LMNAHTTMLNR | |
| SCHEMBL10842332 | 0.70 | GHSR (0.42) | LMNAMLNR | |
| SCHEMBL14250375 | 0.68 | HRH3 (0.35) | — | |
| Hydrochloric Acid SCHEMBL5038229 | 0.68 | HTR2C (0.46) | MLNR | |
| SCHEMBL30497365 | 0.67 | AR (0.34) | — | |
| SCHEMBL30497353 | 0.67 | AR (0.34) | — | |
| SCHEMBL4524731 | 0.67 | GLA (0.46) | GLATSHRSMN1; SMN2LMNA | |
| SCHEMBL12552290 | 0.65 | — | — | |
| SCHEMBL26724598 | 0.64 | LMNA (0.41) | GLATSHRSMN1; SMN2LMNAHTT | |
| SCHEMBL7812982 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090124601-A1 | Tartaric Acid Salts of a Dipeptidyl Peptidase-IV Inhibitor | MERCK & CO., INC. | 2009-05-14 | — | — | US | disclosed |
| US-20090124601-A1 | Tartaric Acid Salts of a Dipeptidyl Peptidase-IV Inhibitor | MERCK & CO., INC. | 2009-05-14 | — | — | US | disclosed |
| US-20090124601-A1 | Tartaric Acid Salts of a Dipeptidyl Peptidase-IV Inhibitor | MERCK & CO., INC. | 2009-05-14 | — | — | US | disclosed |
| WO-2008040995-A9 | INDAZOLES FOR USE AS DPP-IV INHIBITORS | PEAKDALE MOLECULAR LTD (GB) | 2008-12-31 | — | — | WO | disclosed |
| WO-2008040995-A9 | INDAZOLES FOR USE AS DPP-IV INHIBITORS | PEAKDALE MOLECULAR LTD (GB) | 2008-12-31 | — | — | WO | disclosed |
| WO-2008040995-A1 | INDAZOLES FOR USE AS DPP-IV INHIBITORS | PEAKDALE MOLECULAR LIMITED (GB) | 2008-04-10 | — | — | WO | disclosed |
| WO-2008040995-A1 | INDAZOLES FOR USE AS DPP-IV INHIBITORS | PEAKDALE MOLECULAR LIMITED (GB) | 2008-04-10 | — | — | WO | disclosed |
| WO-2006104997-A2 | TARTARIC ACID SALTS OF A DIPEPTIDYL PEPTIDASE-IV INHIBITOR | MERCK & CO., INC. (US) | 2006-10-05 | — | — | WO | disclosed |
| WO-2006065826-A2 | PROCESS TO CHIRAL BETA AMINO ACID DERIVATIVES BY ASYMMETRIC HYDROGENATION | MERCK & CO., INC. (US) | 2006-06-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090124601-A1 | Tartaric Acid Salts of a Dipeptidyl Peptidase-IV Inhibitor | DPP4, DPP3, DPP7 | DPP4 1/4885DPP8 5/4885DPP7 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.