Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.38 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.35 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.35 |
| ▸ | GABRP | O00591 | 1/20 | 0.35 |
| ▸ | GABRD | O14764 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10495701 | 0.75 | GPR17 (0.39) | KEAP1HSD17B10FFAR1NPSR1CA1 | |
| SCHEMBL18249526 | 0.74 | TAAR1 (0.36) | HSD17B10CYP1A2TSHRKMT2A | |
| SCHEMBL10495782 | 0.73 | GPR17 (0.38) | KEAP1LMNAFFAR1NPSR1CYP1A2 | |
| SCHEMBL10495743 | 0.73 | GPR17 (0.39) | FFAR1NPSR1 | |
| SCHEMBL6419512 | 0.70 | SIRT1 (0.39) | KEAP1HSD17B10FFAR1NPSR1CA1 | |
| SCHEMBL7531615 | 0.70 | POLB (0.32) | — | |
| SCHEMBL28830916 | 0.69 | NPSR1 (0.50) | KEAP1LMNAALKBH5SUCNR1EGLN1 | |
| SCHEMBL11407701 | 0.69 | POLB (0.35) | CYP1A2 | |
| SCHEMBL11386667 | 0.67 | KEAP1 (0.41) | KEAP1LMNAALKBH5SUCNR1EGLN1 | |
| SCHEMBL2345633 | 0.67 | FFAR1 (0.43) | KEAP1LMNAALKBH5SUCNR1EGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3027695-A1 | AQUEOUS CLEANING COMPOSITIONS INCLUDING AN ALKYL 3-HYDROXYBUTYRATE | Eastman Chemical Company (US) | 2016-06-08 | — | — | EP | disclosed |
| WO-2015017176-A1 | AQUEOUS CLEANING COMPOSITIONS HAVING ENHANCED PROPERTIES | EASTMAN CHEMICAL COMPANY (US) | 2015-02-05 | — | — | WO | disclosed |
| WO-2015017175-A1 | AQUEOUS CLEANING COMPOSITIONS INCLUDING AN ALKYL 3-HYDROXYBUTYRATE | EASTMAN CHEMICAL COMPANY (US) | 2015-02-05 | — | — | WO | disclosed |
| EP-2664016-A1 | MEMBRANES SUITABLE FOR USE AS SEPARATORS AND ELECTROCHEMICAL CELLS INCLUDING SUCH SEPARATORS | ETV Energy Ltd. (IL) | 2013-11-20 | — | — | EP | disclosed |
| WO-2012095805-A1 | MEMBRANES SUITABLE FOR USE AS SEPARATORS AND ELECTROCHEMICAL CELLS INCLUDING SUCH SEPARATORS | ETV ENERGY LTD. (IL) | 2012-07-19 | — | — | WO | disclosed |
| WO-2009085072-A1 | COMPOSITION COMPRISING CHELATING AGENTS CONTAINING AMIDOXIME COMPOUNDS | EKC TECHNOLOGY, INC (US) | 2009-07-09 | — | — | WO | disclosed |