Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 9/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.39 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.39 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2535698 | 0.78 | SLC22A12 (0.44) | SLC22A12KDM4EMEN1ALDH1A1HPGD | |
| SCHEMBL4143532 | 0.78 | SCN9A (0.42) | SLC22A12KDM4EMEN1ALDH1A1HPGD | |
| SCHEMBL10963864 | 0.73 | CYP11B1 (0.46) | KDM4EMEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL11007176 | 0.73 | KDM4E (0.36) | KDM4EALDH1A1HPGD | |
| SCHEMBL11236954 | 0.70 | KDM4E (0.57) | KDM4EMEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL21340368 | 0.70 | SCN9A (0.43) | SLC22A12SCN9A | |
| SCHEMBL23207342 | 0.70 | ALDH1A1 (0.35) | KDM4EMEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL10964326 | 0.69 | EGFR (0.51) | KDM4EMEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL6283098 | 0.69 | KDM4E (0.46) | KDM4EMEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL10965164 | 0.69 | KDM4E (0.52) | KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3263109-B1 | DRUG FOR PREVENTING AND/OR TREATING DEMENTIA | NAT UNIV CORP TOTTORI UNIV (JP) | 2020-06-17 | — | — | EP | claimed |
| US-20090149452-A1 | XANTHINE OXIDASE INHIBITOR | NIPPON CHEMIPHAR CO., LTD. (JP) | 2009-06-11 | — | — | US | disclosed |
| EP-1911760-A1 | XANTHINE OXIDASE INHIBITOR | Nippon Chemiphar Co., Ltd. (JP) | 2008-04-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090149452-A1 | XANTHINE OXIDASE INHIBITOR | XDH, PNPO, CBR1 | SLC22A12 1556/4885KDM4E 2299/4885MEN1 4779/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.