Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 11/20 | 0.67 |
| ▸ | CHRM3 | P20309 | 6/20 | 0.67 |
| ▸ | ADRB3 | P13945 | 9/20 | 0.60 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4154422 | 0.92 | ADRB2 (0.67) | ADRB2CHRM3ADRB3ADRB1 | |
| SCHEMBL524043 | 0.84 | ADRB2 (0.92) | ADRB2CHRM3ADRB3ADRB1 | |
| SCHEMBL4149830 | 0.83 | ADRB2 (0.59) | ADRB2CHRM3ADRB1 | |
| SCHEMBL13613082 | 0.81 | ADRB2 (0.80) | ADRB2CHRM3ADRB3ADRB1 | |
| Succinic Acid SCHEMBL4141474 | 0.81 | ADRB2 (0.86) | ADRB2CHRM3ADRB3ADRB1 | |
| SCHEMBL4166545 | 0.81 | ADRB2 (0.96) | ADRB2CHRM3ADRB3ADRB1 | |
| SCHEMBL4160120 | 0.80 | ADRB2 (1.00) | ADRB2CHRM3ADRB3ADRB1 | |
| SCHEMBL4145062 | 0.80 | ADRB2 (0.83) | ADRB2CHRM3ADRB3 | |
| SCHEMBL4153768 | 0.80 | ADRB2 (0.99) | ADRB2CHRM3ADRB3 | |
| SCHEMBL4157910 | 0.78 | ADRB3 (0.78) | ADRB2CHRM3ADRB3ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090253739-A1 | Amine Derivatives | PFIZER INC | 2009-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090253739-A1 | Amine Derivatives | HNMT, HRH4, CMA1 | ADRB2 93/4885CHRM3 169/4885ADRB3 108/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.