Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.59 |
| ▸ | BCDIN3D | Q7Z5W3 | 14/20 | 0.50 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4159110 | 0.88 | TRPV1 (0.58) | TRPV1BCDIN3D | |
| SCHEMBL4159117 | 0.83 | TRPV1 (0.47) | TRPV1BCDIN3D | |
| SCHEMBL4162708 | 0.83 | TRPV1 (0.44) | TRPV1BCDIN3D | |
| SCHEMBL4154239 | 0.81 | TRPV1 (0.45) | TRPV1BCDIN3D | |
| SCHEMBL4165766 | 0.81 | TRPV1 (0.44) | TRPV1 | |
| SCHEMBL4165731 | 0.81 | TRPV1 (0.42) | TRPV1BCDIN3D | |
| SCHEMBL4159118 | 0.80 | TRPV1 (0.50) | TRPV1 | |
| SCHEMBL4167024 | 0.78 | TRPV1 (0.54) | TRPV1 | |
| SCHEMBL4166871 | 0.77 | TRPV1 (0.59) | TRPV1 | |
| SCHEMBL4158459 | 0.77 | TRPV1 (0.50) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090156598-A1 | Imidazolopyrimidine modulators of TRPV1 | JANSSEN PHARMACEUTICA NV (BE) | 2009-06-18 | — | — | US | claimed |
| US-20090156598-A1 | Imidazolopyrimidine modulators of TRPV1 | JANSSEN PHARMACEUTICA NV (BE) | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156598-A1 | Imidazolopyrimidine modulators of TRPV1 | TRPV1, TRPV2, TRPV5 | TRPV1 1/4885BCDIN3D 1708/4885FLT3 2949/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.