Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.79 |
| ▸ | HTT | P42858 | 4/20 | 0.69 |
| ▸ | RAB9A | P51151 | 4/20 | 0.69 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.66 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9010473 | 0.88 | ALDH1A1 (0.79) | ALDH1A1HTTRAB9ANPSR1KDM4E | |
| SCHEMBL7934013 | 0.88 | ALDH1A1 (0.79) | ALDH1A1HTTRAB9ANPSR1KDM4E | |
| SCHEMBL13975009 | 0.86 | ALDH1A1 (0.77) | ALDH1A1HTTRAB9ANPSR1KDM4E | |
| SCHEMBL3516960 | 0.84 | ALDH1A1 (0.74) | ALDH1A1HTTRAB9ANPSR1KDM4E | |
| SCHEMBL8699832 | 0.84 | ALDH1A1 (0.73) | ALDH1A1HTTRAB9ANPSR1KDM4E | |
| SCHEMBL8696809 | 0.82 | ALDH1A1 (0.71) | ALDH1A1HTTRAB9ANPSR1KDM4E | |
| SCHEMBL8696284 | 0.82 | ALDH1A1 (0.72) | ALDH1A1HTTRAB9ANPSR1KDM4E | |
| SCHEMBL18788436 | 0.80 | ALDH1A1 (0.51) | ALDH1A1HTTRAB9ANPSR1KDM4E | |
| SCHEMBL8693125 | 0.80 | ALDH1A1 (0.70) | ALDH1A1HTTRAB9ANPSR1KDM4E | |
| SCHEMBL5332408 | 0.80 | ALDH1A1 (0.85) | ALDH1A1HTTRAB9ANPSR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090176825-A1 | PROLYL HYDROXYLASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION | 2009-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090176825-A1 | PROLYL HYDROXYLASE INHIBITORS | HIF1AN, EGLN2, EGLN3 | ALDH1A1 319/4885HTT 1880/4885RAB9A 4158/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.