Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.36 |
| ▸ | CBL | P22681 | 2/20 | 0.35 |
| ▸ | CBLB | Q13191 | 2/20 | 0.35 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.35 |
| ▸ | GUCY1B1 | Q02153 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13696729 | 0.82 | CYP1A2 (0.43) | CYP1A2KDM4EALDH1A1HPGDL3MBTL1 | |
| SCHEMBL4924175 | 0.82 | CYP1A2 (0.44) | CYP1A2KDM4EMAPTMEN1KMT2A | |
| SCHEMBL13697339 | 0.79 | CYP1A2 (0.39) | CYP1A2KDM4EL3MBTL1MAPTMEN1 | |
| SCHEMBL13696718 | 0.77 | PTGER1 (0.46) | CYP1A2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL13696906 | 0.77 | MAOB (0.44) | CYP1A2KDM4EGAAL3MBTL1MAPT | |
| SCHEMBL4158553 | 0.77 | PTGER1 (0.39) | CYP1A2KDM4EALDH1A1L3MBTL1NPSR1 | |
| SCHEMBL4158397 | 0.77 | KDM4E (0.39) | KDM4EALDH1A1HPGDGAAL3MBTL1 | |
| SCHEMBL4916416 | 0.76 | PTGER1 (0.59) | CYP3A4CYP2C9CYP2C19PTGER1 | |
| SCHEMBL4153864 | 0.76 | PTGER1 (0.41) | CYP1A2ALDH1A1L3MBTL1CYP3A4CYP2C9 | |
| SCHEMBL4154724 | 0.76 | PTGER1 (0.47) | CYP1A2CYP3A4CYP2C9CYP2C19PTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090227591-A1 | Cyclopentene compounds | GLAXO GROUP LIMITED (GB) | 2009-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090227591-A1 | Cyclopentene compounds | C1R, CYP1B1, ADORA2B | CYP1A2 72/4885KDM4E 2449/4885ALDH1A1 1534/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.