Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | PDK1 | Q15118 | 4/20 | 0.48 |
| ▸ | PDK2 | Q15119 | 4/20 | 0.48 |
| ▸ | PDK3 | Q15120 | 4/20 | 0.48 |
| ▸ | PDK4 | Q16654 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.47 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.47 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | SPR | P35270 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4161521 | 0.92 | PARP10 (0.49) | RAB9ANPC1ATMPDK1PDK2 | |
| SCHEMBL4143175 | 0.87 | HSP90AA1 (0.62) | RAB9ANPC1ATMMAPTHSP90AA1 | |
| SCHEMBL4151908 | 0.80 | HSD11B1 (0.55) | RAB9ANPC1ATMMAPTHSP90AA1 | |
| SCHEMBL6208828 | 0.78 | HSD11B1 (0.68) | GAA | |
| SCHEMBL2937126 | 0.75 | RAB9A (0.67) | RAB9ANPC1ATMMAPTPROKR1 | |
| SCHEMBL2937123 | 0.75 | RAB9A (0.67) | RAB9ANPC1ATMMAPTPROKR1 | |
| SCHEMBL30693168 | 0.74 | RAB9A (0.61) | RAB9ANPC1ATMMAPTPROKR1 | |
| SCHEMBL16600231 | 0.74 | RAB9A (0.61) | RAB9ANPC1ATMMAPTPROKR1 | |
| SCHEMBL4155107 | 0.74 | HSP90AA1 (0.50) | PDK1PDK2PDK3PDK4HSP90AA1 | |
| SCHEMBL4159603 | 0.73 | HSP90AA1 (0.63) | RAB9ANPC1PDK1PDK2PDK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090215742-A1 | AMIDE RESORCINOL COMPOUNDS | PFIZER, INC. | 2009-08-27 | — | — | US | claimed |
| US-20090215742-A1 | AMIDE RESORCINOL COMPOUNDS | PFIZER, INC. | 2009-08-27 | — | — | US | disclosed |
| US-20090215742-A1 | AMIDE RESORCINOL COMPOUNDS | PFIZER, INC. | 2009-08-27 | — | — | US | disclosed |
| US-20090215742-A1 | AMIDE RESORCINOL COMPOUNDS | PFIZER, INC. | 2009-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090215742-A1 | AMIDE RESORCINOL COMPOUNDS | HSP90AB1, HSP90AA1, HSP90AB2P | RAB9A 588/4885NPC1 521/4885ATM 3686/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.