Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | ERN1 | O75460 | 2/20 | 0.38 |
| ▸ | CES2 | O00748 | 2/20 | 0.37 |
| ▸ | CES1 | P23141 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.31 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.30 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31685229 | 1.00 | CYP2C9 (0.46) | CYP2C9CYP3A4CYP2C19CYP2D6ERN1 | |
| SCHEMBL12235261 | 0.85 | ERN1 (0.42) | CYP2C9CYP3A4CYP2C19CYP2D6ERN1 | |
| SCHEMBL1816745 | 0.82 | ERN1 (0.43) | CYP2C9CYP3A4CYP2C19CYP2D6ERN1 | |
| SCHEMBL2891346 | 0.80 | CYP2C9 (0.41) | CYP2C9CYP3A4CYP2C19CYP2D6ERN1 | |
| SCHEMBL415661 | 0.80 | ERN1 (0.42) | CYP2C9CYP3A4CYP2C19CYP2D6ERN1 | |
| SCHEMBL11992946 | 0.80 | CYP2C9 (0.41) | CYP2C9CYP3A4CYP2C19CYP2D6ERN1 | |
| SCHEMBL1197434 | 0.80 | CYP2C9 (0.45) | CYP2C9CYP3A4CYP2C19CYP2D6ERN1 | |
| SCHEMBL615646 | 0.80 | ALDH1A1 (0.44) | CYP2C9CYP3A4CYP2C19CYP2D6ERN1 | |
| SCHEMBL658249 | 0.80 | CYP2C9 (0.41) | CYP2C9CYP3A4CYP2C19CYP2D6ERN1 | |
| SCHEMBL1359122 | 0.80 | ALDH1A1 (0.50) | CYP2C9CYP3A4CYP2C19CYP2D6ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 274 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118459422-A | Thiazole thiazolinone compound containing multiple halogen atoms and preparation method thereof | 南京工业大学 | 2024-08-09 | — | — | CN | claimed |
| CN-118459420-A | Thiazolinone compound containing multiple halogen atoms and preparation method thereof | 南京工业大学 | 2024-08-09 | — | — | CN | claimed |
| EP-1506176-B1 | AMINOINDAZOLE DERIVATIVES ACTIVE AS KINASE INHIBITORS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | PFIZER ITALIA SRL (IT) | 2013-04-24 | — | — | EP | claimed |
| EP-1306380-B1 | NOVEL EXPANDED PORPHYRINS AND PROCESS FOR THE SYNTHESIS THEREOF | JAPAN SCIENCE & TECH AGENCY (JP) | 2008-12-17 | — | — | EP | claimed |
| US-20060084176-A1 | Detection of uronium salts | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2006-04-20 | — | — | US | claimed |
| US-6822092-B2 | LARGER CYCLIC NITROGEN-NETWORK, RED-SHIFTED ABSORPTION BANDS, MORE FLEXIBLE CONFORMATION OF THE MACROCYCLES, AND COORDINATION ABILITY OF MORE THAN TWO METAL IONS | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2004-11-23 | — | — | US | claimed |
| EP-1390336-A1 | METHOD FOR PRODUCING AROMATIC ALDEHYDES AND KETONES BY THE CATALYTIC OXIDATION OF ALKYL-AROMATIC COMPOUNDS | DSM Fine Chemicals Austria Nfg GmbH & Co KG (AT) | 2004-02-25 | — | — | EP | claimed |
| US-20030162963-A1 | Novel expanded porphyrins and process for the synthesis thereof | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2003-08-28 | — | — | US | claimed |
| EP-1306380-A1 | NOVEL EXPANDED PORPHYRINS AND PROCESS FOR THE SYNTHESIS THEREOF | Japan Science and Technology Corporation (JP) | 2003-05-02 | — | — | EP | claimed |
| WO-2002096849-A1 | METHOD FOR PRODUCING AROMATIC ALDEHYDES AND KETONES BY THE CATALYTIC OXIDATION OF ALKYL-AROMATIC COMPOUNDS | DSM FINE CHEMICALS AUSTRIA NFG GMBH & CO KG (AT) | 2002-12-05 | — | — | WO | claimed |
| EP-0725787-A1 | ACTIVATED NUCLEOSIDE PHOSPHORAMIDITES AND METHODS FOR THE PREPARATION AND USE THEREOF | BECKMAN INSTRUMENTS, INC. (US) | 1996-08-14 | — | — | EP | claimed |
| WO-1996006853-A1 | ACTIVATED NUCLEOSIDE PHOSPHORAMIDITES AND METHODS FOR THE PREPARATION AND USE THEREOF | BECKMAN INSTRUMENTS, INC. (US) | 1996-03-07 | — | — | WO | claimed |
| US-12338241-B2 | Bicyclic sulfones and sulfoxides and methods of use thereof | GENENTECH, INC. (US) | 2025-06-24 | — | — | US | disclosed |
| CN-119613408-A | Bicyclic ketone compounds and methods of use thereof | 豪夫迈·罗氏有限公司 | 2025-03-14 | — | — | CN | disclosed |
| WO-2024259241-A1 | 5-HT2A RECEPTOR MODULATORS AND METHODS OF USE THEREOF | Transneural Therapeutics, Inc. (US) | 2024-12-19 | — | — | WO | disclosed |
| CN-110914271-B | Bicyclic ketone compounds and methods of use thereof | 豪夫迈·罗氏有限公司 | 2024-12-10 | — | — | CN | disclosed |
| WO-1996006853-A1 | ACTIVATED NUCLEOSIDE PHOSPHORAMIDITES AND METHODS FOR THE PREPARATION AND USE THEREOF | BECKMAN INSTRUMENTS, INC. (US) | 1996-03-07 | — | — | WO | disclosed |
| US-4618678-A | 4-(2,3-dichloro-6-fluorophenyl)-1,4,5,6,7,8-hexahydro-2-methyl-5-oxo-1,7-naphthyridine-3-carboxylic acid 2-(2,3-dichlorophenoxy)ethyl ester | AMERICAN HOME PRODUCTS CORPORATION (US) | 1986-10-21 | — | — | US | disclosed |
| US-4596873-A | 1,4,5,6,7,8-Hexahydro-2-alkyl-4-aryl-5-oxo-1,7-naphthyridine-3-carboxylic acid aromatic esters and pharmaceutically acceptable acid addition salts thereof useful as antihypertensive agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1986-06-24 | — | — | US | disclosed |
| EP-0174131-A2 | Dihydropyridines, processes and intermediates for their production, and pharmaceutical formulations containing them | FISONS plc (GB) | 1986-03-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12338241-B2 | Bicyclic sulfones and sulfoxides and methods of use thereof | RB1, CCNE2, RPS3A | CYP2C9 1164/4885CYP3A4 1269/4885CYP2C19 915/4885 |
| US-20030162963-A1 | Novel expanded porphyrins and process for the synthesis thereof | AAAS, PAM, AHR | CYP2C9 150/4885CYP3A4 282/4885CYP2C19 181/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.