Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.46 |
| ▸ | HPGD | P15428 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.40 |
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 10/20 | 0.39 |
| ▸ | RAB9A | P51151 | 10/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | STAT1 | P42224 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.36 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8415489 | 0.86 | KDM4E (0.45) | PPARGPPARAKDM4EHPGDALDH1A1 | |
| SCHEMBL26383710 | 0.85 | ESR1 (0.40) | PPARGPPARAKDM4EHPGDALDH1A1 | |
| SCHEMBL2548304 | 0.84 | KDM4E (0.47) | PPARGPPARAKDM4EHPGDALDH1A1 | |
| SCHEMBL29351747 | 0.82 | PPARG (0.41) | PPARGPPARAKDM4EHPGDALDH1A1 | |
| SCHEMBL3680277 | 0.82 | PPARG (0.41) | PPARGPPARAKDM4EHPGDALDH1A1 | |
| SCHEMBL29903 | 0.81 | NPC1 (0.46) | PPARGPPARAKDM4EHPGDALDH1A1 | |
| SCHEMBL29354035 | 0.81 | NPC1 (0.46) | PPARGPPARAKDM4EHPGDALDH1A1 | |
| SCHEMBL9488921 | 0.81 | ALDH1A1 (0.44) | PPARGPPARAKDM4EHPGDALDH1A1 | |
| SCHEMBL6445924 | 0.81 | KDM4E (0.52) | PPARGPPARAKDM4EHPGDALDH1A1 | |
| SCHEMBL31212619 | 0.80 | NPC1 (0.39) | PPARGPPARAKDM4EHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-62240349-A | — | — | None | — | — | JP | disclosed |
| JP-11130955-A | — | — | None | — | — | JP | disclosed |
| US-20090137771-A1 | RESIN COMPOSITION | KYOWA HAKKO CHEMICAL CO., LTD. (JP) | 2009-05-28 | — | — | US | disclosed |
| JP-H11130955-A | POLYCARBONATE COMPOSITION CONTAINING POLYESTER RESIN AND ULTRAVIOLET ABSORBER | GENERAL ELECTRIC CO <GE> | 1999-05-18 | — | — | JP | disclosed |
| EP-0276649-B1 | Curable fluor-containing copolymers as binders in weatherproof coatings | HOECHST AG (DE) | 1993-11-03 | — | — | EP | disclosed |
| US-5086095-A | Weather stabilizer, acrylic resin, fluororesin | POLYPLASTICS CO., LTD. (JP) | 1992-02-04 | — | — | US | disclosed |
| EP-0276649-A2 | Curable fluor-containing copolymers as binders in weatherproof coatings | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-08-03 | — | — | EP | disclosed |
| JP-S62240349-A | LIGHT-RESISTANT POLYESTER COMPOSITION | UNITIKA LTD | 1987-10-21 | — | — | JP | disclosed |