SCHEMBL415914

SCHEMBL415914

COc1ccc(-c2cc(N)ccc2-c2ccc(N)cc2-c2ccc(OC)cc2)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.58
MAPK1 P28482 2/20 0.58
ALDH1A1 P00352 4/20 0.56
CYP3A4 P08684 3/20 0.56
APP P05067 2/20 0.52
KDM4E B2RXH2 3/20 0.49
RAB9A P51151 3/20 0.49
NPC1 O15118 2/20 0.49
MAPT P10636 4/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
TP53 P04637 2/20 0.49
HPGD P15428 2/20 0.49
NFKB1 P19838 1/20 0.49
NFKB2 Q00653 1/20 0.49
RELA Q04206 1/20 0.49
HSD17B10 Q99714 1/20 0.49
ABL1 P00519 1/20 0.48
ABCB1 P08183 1/20 0.48
BCR P11274 1/20 0.48
NR4A1 P22736 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10805501 0.96 TDP1 (0.58) TDP1MAPK1ALDH1A1CYP3A4APP
SCHEMBL29352352 0.94 TDP1 (0.61) TDP1MAPK1ALDH1A1CYP3A4APP
SCHEMBL1444781 0.94 TDP1 (0.61) TDP1MAPK1ALDH1A1CYP3A4APP
SCHEMBL15271344 0.89 ABL1 (0.56) TDP1MAPK1ALDH1A1CYP3A4APP
SCHEMBL28930384 0.88 ABL1 (0.59) TDP1MAPK1ALDH1A1CYP3A4APP
SCHEMBL453782 0.86 TDP1 (0.56) TDP1MAPK1ALDH1A1CYP3A4APP
SCHEMBL6011274 0.86 TDP1 (0.56) TDP1MAPK1ALDH1A1CYP3A4APP
SCHEMBL5685506 0.85 MAPK1 (0.54) TDP1MAPK1ALDH1A1CYP3A4APP
Hydrochloric Acid SCHEMBL6574161 0.85 ALDH1A1 (0.57) TDP1MAPK1ALDH1A1CYP3A4APP
SCHEMBL13550581 0.85 TDP1 (0.54) TDP1MAPK1ALDH1A1CYP3A4APP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2596509-B1 DYE SOLAR CELL WITH IMPROVED STABILITY BASF SE (DE) 2019-06-19 EP disclosed
US-20170082426-A1 DETECTOR FOR OPTICALLY DETECTING AT LEAST ONE OBJECT BASF SE (DE) 2017-03-23 US disclosed
US-9595678-B2 Dye solar cell with improved stability BASF SE (DE) 2017-03-14 US disclosed
EP-3029485-A1 DETECTOR FOR OPTICALLY DETECTING AT LEAST ONE OBJECT BASF SE (DE) 2016-06-08 EP disclosed
EP-2676102-B1 DETECTOR FOR OPTICALLY DETECTING AT LEAST ONE OBJECT BASF SE (DE) 2016-04-20 EP disclosed
US-9087991-B2 Photovoltaic element BASF SE (DE) 2015-07-21 US disclosed
US-20150124268-A1 DETECTOR FOR OPTICALLY DETECTING AT LEAST ONE OBJECT BASF SE (DE) 2015-05-07 US disclosed
US-9001029-B2 Detector for optically detecting at least one object BASF SE (DE) 2015-04-07 US disclosed
US-20140130870-A1 USE OF TRIARYLAMINE DERIVATIVES AS HOLE-CONDUCTING MATERIALS IN ORGANIC SOLAR CELLS AND ORGANIC SOLAR CELLS CONTAINING SAID TRIARYLAMINE DERIVATIVES BASF SE (DE) 2014-05-15 US disclosed
EP-2676102-A1 DETECTOR FOR OPTICALLY DETECTING AT LEAST ONE OBJECT BASF SE (DE) 2013-12-25 EP disclosed
EP-2671271-A1 PHOTOVOLTAIC ELEMENT BASF SE (DE) 2013-12-11 EP disclosed
US-20120279566-A1 PHOTOVOLTAIC ELEMENT WITH INCREASED LONG-TERM STABILITY BASF SE (DE) 2012-11-08 US disclosed
WO-2012110924-A1 DETECTOR FOR OPTICALLY DETECTING AT LEAST ONE OBJECT BASF SE (DE) 2012-08-23 WO disclosed
US-20120206336-A1 DETECTOR FOR OPTICALLY DETECTING AT LEAST ONE OBJECT BASF SE (DE) 2012-08-16 US disclosed
WO-2012104742-A1 PHOTOVOLTAIC ELEMENT BASF SE (DE) 2012-08-09 WO disclosed
US-20120192945-A1 PHOTOVOLTAIC ELEMENT BASF SE (DE) 2012-08-02 US disclosed
US-20120017995-A1 DYE SOLAR CELL WITH IMPROVED STABILITY BASF SE (DE) 2012-01-26 US disclosed
EP-2399305-A1 USE OF TRIARYLAMINE DERIVATIVES AS HOLE-CONDUCTING MATERIALS IN ORGANIC SOLAR CELLS AND ORGANIC SOLAR CELLS CONTAINING SAID TRIARYLAMINE DERIVATIVES BASF SE (DE) 2011-12-28 EP disclosed
US-20110297235-A1 USE OF TRIARYLAMINE DERIVATIVES AS HOLE-CONDUCTING MATERIALS IN ORGANIC SOLAR CELLS AND ORGANIC SOLAR CELLS CONTAINING SAID TRIARYLAMINE DERIVATIVES BASF SE (DE) 2011-12-08 US disclosed
WO-2010094636-A1 USE OF TRIARYLAMINE DERIVATIVES AS HOLE-CONDUCTING MATERIALS IN ORGANIC SOLAR CELLS AND ORGANIC SOLAR CELLS CONTAINING SAID TRIARYLAMINE DERIVATIVES BASF SE (DE) 2010-08-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110297235-A1 USE OF TRIARYLAMINE DERIVATIVES AS HOLE-CONDUCTING MATERIALS IN ORGANIC SOLAR CELLS AND ORGANIC SOLAR CELLS CONTAINING SAID TRIARYLAMINE DERIVATIVES NR2E3, NR0B2, AHR TDP1 2814/4885MAPK1 3579/4885ALDH1A1 1407/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.