SCHEMBL4159183

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4159182	1.00	DRD4 (0.50)	DRD4SIGMAR1RORCBCHEACHE
	SCHEMBL11958053	0.94	DRD4 (0.56)	DRD4SIGMAR1BCHEACHEBACE1
	SCHEMBL15315675	0.83	SIGMAR1 (0.52)	DRD4SIGMAR1BCHEACHEBACE1
	SCHEMBL13699526	0.83	SIGMAR1 (0.52)	DRD4SIGMAR1BCHEACHEBACE1
	SCHEMBL11958071	0.81	CNR1 (0.53)	DRD4SIGMAR1BCHEACHEBACE1
	SCHEMBL82746	0.79	RORC (0.52)	SIGMAR1RORCBCHEACHEBACE1
	SCHEMBL11957721	0.79	CNR1 (0.59)	DRD4SIGMAR1ALDH1A1CYP3A4CYP2D6
	SCHEMBL11957717	0.78	SIGMAR1 (0.51)	DRD4SIGMAR1BCHEACHEBACE1
	SCHEMBL588395	0.76	DRD4 (0.56)	DRD4SIGMAR1BCHEACHEBACE1
	Hydrochloric Acid SCHEMBL3275474	0.76	SIGMAR1 (0.55)	DRD4SIGMAR1BCHEACHEBACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.