SCHEMBL4159283

SCHEMBL4159283

CCCC1CCC([C@H]2CC[C@H](C(=O)O)CC2)CC1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.50
PLG P00747 1/20 0.50
PLAT P00750 1/20 0.50
TLR4 O00206 2/20 0.43
ANPEP P15144 1/20 0.41
ENPEP Q07075 1/20 0.41
CYP2C9 P11712 3/20 0.39
POLB P06746 1/20 0.38
HPGD P15428 1/20 0.38
TP53 P04637 1/20 0.38
MAPT P10636 2/20 0.37
ALDH1A1 P00352 2/20 0.37
PKM P14618 1/20 0.37
HTT P42858 2/20 0.37
MAPK1 P28482 1/20 0.37
KMT2A Q03164 3/20 0.36
MEN1 O00255 2/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C19 P33261 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4159289 1.00 LMNA (0.50) LMNAPLGPLATTLR4ANPEP
SCHEMBL1310398 1.00 LMNA (0.50) LMNAPLGPLATTLR4ANPEP
SCHEMBL10797746 1.00 LMNA (0.50) LMNAPLGPLATTLR4ANPEP
SCHEMBL10797749 1.00 LMNA (0.50) LMNAPLGPLATTLR4ANPEP
SCHEMBL10707221 1.00 LMNA (0.50) LMNAPLGPLATTLR4ANPEP
SCHEMBL3275198 1.00 LMNA (0.50) LMNAPLGPLATTLR4ANPEP
Hydrochloric Acid SCHEMBL10485590 0.98 LMNA (0.48) LMNAPLGPLATTLR4ANPEP
Hydrochloric Acid SCHEMBL10484641 0.98 LMNA (0.48) LMNAPLGPLATTLR4ANPEP
SCHEMBL3512672 0.94 LMNA (0.56) LMNAPLGPLATANPEPENPEP
SCHEMBL223128 0.94 LMNA (0.56) LMNAPLGPLATANPEPENPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8293146-B2 Optical film and phase difference plate, and liquid crystal compound FUJIFILM CORPORATION (JP) 2012-10-23 US disclosed
US-20090159857-A1 OPTICAL FILM AND PHASE DIFFERENCE PLATE, AND LIQUID CRYSTAL COMPOUND FUJIFILM CORPORATION (JP) 2009-06-25 US disclosed
WO-2007091716-A1 OPTICAL FILM AND PHASE DIFFERENCE PLATE, AND LIQUID CRYSTAL COMPOUND FUJIFILM CORPORATION (JP) 2007-08-16 WO disclosed
US-6506462-B1 Liquid crystalline medium MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2003-01-14 US disclosed
US-6406761-B1 MIXTURE OF POLAR COMPOUNDS MERCK PATENTS GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) 2002-06-18 US disclosed
EP-0842238-B1 LIQUID CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2001-11-21 EP disclosed
EP-0842238-A1 LIQUID CRYSTALLINE MEDIUM MERCK PATENT GmbH (DE) 1998-05-20 EP disclosed
WO-1997005214-A1 LIQUID CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 1997-02-13 WO disclosed
US-4871469-A TRIFLUOROTOLUENE DERIVATIVES BESCRANKTER HAFTUNG (DE) 1989-10-03 US disclosed
US-4617140-A Bicyclohexyl derivatives MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1986-10-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090159857-A1 OPTICAL FILM AND PHASE DIFFERENCE PLATE, AND LIQUID CRYSTAL COMPOUND NOM1, CRYZ, CNN2 LMNA 538/4885PLG 2924/4885PLAT 4273/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.