Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | STAT1 | P42224 | 1/20 | 0.56 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.56 |
| ▸ | RELA | Q04206 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.53 |
| ▸ | ACHE | P22303 | 5/20 | 0.53 |
| ▸ | GLA | P06280 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | CASP1 | P29466 | 2/20 | 0.53 |
| ▸ | CASP7 | P55210 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.53 |
| ▸ | NQO2 | P16083 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4163690 | 0.92 | HPGD (0.51) | HPGDRAB9ANPC1NFKB1STAT1 | |
| SCHEMBL4163106 | 0.91 | KDM4E (0.53) | HPGDRAB9ANPC1NFKB1STAT1 | |
| SCHEMBL4157747 | 0.87 | HPGD (0.47) | HPGDRAB9ANPC1NFKB1STAT1 | |
| SCHEMBL4164352 | 0.80 | ACHE (0.52) | HPGDRAB9ANPC1NFKB1STAT1 | |
| SCHEMBL13696992 | 0.77 | HSD17B10 (0.50) | HPGDRAB9ANPC1KDM4EACHE | |
| Aminacrine SCHEMBL14999 | 0.73 | HSD17B10 (1.00) | HPGDRAB9ANFKB1KDM4EACHE | |
| Aminacrine SCHEMBL29354393 | 0.73 | HSD17B10 (1.00) | HPGDRAB9ANFKB1KDM4EACHE | |
| Aminacrine SCHEMBL12478613 | 0.73 | KDM4E (0.67) | HPGDRAB9AKDM4EACHEGLA | |
| SCHEMBL15761576 | 0.73 | KDM4E (0.67) | HPGDRAB9AKDM4EACHEGLA | |
| SCHEMBL11055652 | 0.73 | ACHE (0.67) | HPGDRAB9AKDM4EACHEGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9127164-B2 | Fluorescent dyes and uses thereof | ALMAC SCIENCES (SCOTLAND) LIMITED (GB) | 2015-09-08 | — | — | US | disclosed |
| EP-1940965-B1 | NOVEL FLUORESCENT DYES AND USES THEREOF | ALMAC SCIENCES SCOTLAND LTD (GB) | 2014-03-26 | — | — | EP | disclosed |
| US-20090226940-A1 | NOVEL FLUORESCENT DYES AND USES THEREOF | ITI SCOTLAND LIMITED (GB) | 2009-09-10 | — | — | US | disclosed |
| EP-1940965-A2 | NOVEL FLUORESCENT DYES AND USES THEREOF | ITI Scotland Limited (GB) | 2008-07-09 | — | — | EP | disclosed |
| WO-2007049057-A2 | NOVEL FLUORESCENT DYES AND USES THEREOF | ITI SCOTLAND LIMITED (GB) | 2007-05-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090226940-A1 | NOVEL FLUORESCENT DYES AND USES THEREOF | ACR, ANXA5, GLB1 | HPGD 2543/4885RAB9A 1712/4885NPC1 1097/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.