Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Monoethanolamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 3/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1878004 | 0.84 | CA1 (0.46) | ALDH1A1RECQLLTA4HCA1CA2 | |
| Monoethanolamine SCHEMBL9783347 | 0.82 | ALDH1A1 (0.40) | ALDH1A1TAAR1RECQLLTA4HPLA2G2A | |
| SCHEMBL9443206 | 0.82 | CA1 (0.44) | ALDH1A1RECQLLTA4HCA1CA2 | |
| SCHEMBL9443046 | 0.80 | CA1 (0.43) | ALDH1A1RECQLLTA4HCA1CA2 | |
| SCHEMBL9443233 | 0.80 | CA1 (0.43) | ALDH1A1RECQLLTA4HCA1CA2 | |
| Ammonia Solution, Strong SCHEMBL9443078 | 0.80 | CA1 (0.43) | ALDH1A1RECQLLTA4HCA1CA2 | |
| SCHEMBL27607789 | 0.79 | TAAR1 (0.39) | ALDH1A1TAAR1RECQLLTA4HPLA2G2A | |
| SCHEMBL5377366 | 0.78 | HRH1 (0.41) | TAAR1LTA4HPLA2G2AHRH1CYP2A6 | |
| Ammonia Solution, Strong SCHEMBL9443055 | 0.78 | CA1 (0.41) | ALDH1A1RECQLLTA4HCA1CA2 | |
| SCHEMBL28346397 | 0.78 | ALDH1A1 (0.52) | ALDH1A1TAAR1RECQLLTA4HCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190072493-A1 | DEVICE AND METHOD FOR ON-CHIP CHEMICAL SEPARATION AND DETECTION | OREGON STATE UNIVERSITY (US) | 2019-03-07 | — | — | US | disclosed |
| US-20170281702-A1 | METHOD OF ISOLATING ANTI-VIRAL INGREDIENTS FROM BAPHICACANTHUS CUSIA, COMPOSITIONS COMPRISING THEM AND THEIR MEDICAL USE | MACAU UNIVERSITY OF SCIENCE AND TECHNOLOGY (MO) | 2017-10-05 | — | — | US | disclosed |
| EP-1991852-B1 | METHODS FOR IDENTIFYING A CELL PHENOTYPE | ZETIQ TECHNOLOGIES LTD (IL) | 2015-07-01 | — | — | EP | disclosed |
| US-8343733-B2 | Methods and compositions for identifying a cell phenotype | ZETIQ TECHNOLOGIES LTD. (IL) | 2013-01-01 | — | — | US | disclosed |
| US-20090117610-A1 | Methods and Compositions for Identifying a Cell Phenotype | ZETIQ TECHNOLOGIES LTD. (IL) | 2009-05-07 | — | — | US | disclosed |
| EP-1991852-A2 | METHODS AND COMPOSITIONS FOR IDENTIFYING A CELL PHENOTYPE | Zetiq Technologies Ltd. (IL) | 2008-11-19 | — | — | EP | disclosed |
| WO-2007102146-A2 | METHODS AND COMPOSITIONS FOR IDENTIFYING A CELL PHENOTYPE | ZETIQ TECHNOLOGIES LTD. (IL) | 2007-09-13 | — | — | WO | disclosed |
| EP-0122009-B1 | ELECTROCHEMICAL DETECTION SYSTEM | ESA, Inc. (US) | 1990-07-18 | — | — | EP | disclosed |
| EP-0371517-A1 | Electrochemical detection system | ESA, Inc. (US) | 1990-06-06 | — | — | EP | disclosed |
| US-4511659-A | Liquid chromatograph with electrochemical detector and method | ESA, INC. (US) | 1985-04-16 | — | — | US | disclosed |
| EP-0122009-A2 | Electrochemical detection system | ESA, Inc. (US) | 1984-10-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170281702-A1 | METHOD OF ISOLATING ANTI-VIRAL INGREDIENTS FROM BAPHICACANTHUS CUSIA, COMPOSITIONS COMPRISING THEM AND THEIR MEDICAL USE | LSS, UGT1A7, LARP7 | ALDH1A1 1377/4885TAAR1 4187/4885RECQL 2531/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.