Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.35 |
| ▸ | IL1R1 | P14778 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Monoethanolamine SCHEMBL4159313 | 0.78 | ALDH1A1 (0.43) | HRH1TAAR1CYP2A6HTR2ASMN1; SMN2 | |
| SCHEMBL6229390 | 0.75 | KDM4E (0.56) | HRH1TAAR1SMN1; SMN2LTA4HPLA2G2A | |
| SCHEMBL1878004 | 0.75 | CA1 (0.46) | LTA4H | |
| SCHEMBL9443206 | 0.73 | CA1 (0.44) | LTA4H | |
| SCHEMBL7065793 | 0.73 | CA2 (0.43) | SMN1; SMN2LTA4H | |
| SCHEMBL14686024 | 0.72 | ALDH1A1 (0.42) | SMN1; SMN2 | |
| SCHEMBL9443233 | 0.71 | CA1 (0.43) | LTA4H | |
| SCHEMBL9443046 | 0.71 | CA1 (0.43) | LTA4H | |
| Ammonia Solution, Strong SCHEMBL9443078 | 0.71 | CA1 (0.43) | LTA4H | |
| SCHEMBL27607789 | 0.71 | TAAR1 (0.39) | HRH1TAAR1LTA4HPLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7217701-B2 | Intracellular calcium concentration increase inhibitors | KATSUHIKO MIKOSHIBA (JP) | 2007-05-15 | — | — | US | disclosed |