SCHEMBL4159724

SCHEMBL4159724

Cc1ccccc1C(=O)NC(C)S

nearest known ligand 0.55

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.53
CYP1A2 P05177 1/20 0.50
CYP2D6 P10635 1/20 0.50
CYP2C19 P33261 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.49
POLB P06746 1/20 0.47
TYK2 P29597 1/20 0.47
THRB P10828 2/20 0.47
ALDH1A1 P00352 2/20 0.47
L3MBTL1 Q9Y468 2/20 0.47
LMNA P02545 2/20 0.47
NPC1 O15118 2/20 0.46
RAB9A P51151 2/20 0.46
GAA P10253 1/20 0.46
MEN1 O00255 1/20 0.46
ALOX12 P18054 1/20 0.46
KMT2A Q03164 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL394511 0.85 HPGD (0.56) HPGDCYP1A2CYP2D6CYP2C19SMN1; SMN2
SCHEMBL4168620 0.83 HPGD (0.55) HPGDCYP1A2CYP2D6CYP2C19SMN1; SMN2
SCHEMBL24567577 0.81 HPGD (0.53) HPGDCYP1A2CYP2D6CYP2C19SMN1; SMN2
SCHEMBL7150322 0.81 ALDH1A1 (0.52) HPGDCYP1A2POLBALDH1A1LMNA
SCHEMBL24571390 0.81 HPGD (0.53) HPGDCYP1A2CYP2D6CYP2C19SMN1; SMN2
SCHEMBL15271735 0.81 GLA (0.55) HPGDCYP1A2CYP2D6CYP2C19SMN1; SMN2
SCHEMBL24093941 0.80 HPGD (0.51) HPGDCYP1A2CYP2D6CYP2C19SMN1; SMN2
SCHEMBL12126797 0.80 HPGD (0.51) HPGDCYP1A2CYP2D6CYP2C19SMN1; SMN2
SCHEMBL23689650 0.79 MEN1 (0.73) HPGDCYP1A2CYP2D6CYP2C19POLB
SCHEMBL13162410 0.79 MEN1 (0.54) HPGDCYP1A2CYP2D6CYP2C19SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090030099-A1 FOAM COMPOSITION AND FOAM THE YOKOHAMA RUBBER CO., LTD. (JP) 2009-01-29 US disclosed