SCHEMBL7150322

SCHEMBL7150322

CC(S)NC(=O)c1ccccc1C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.52
ALOX15 P16050 1/20 0.52
KMT2A Q03164 5/20 0.49
MEN1 O00255 2/20 0.49
POLB P06746 1/20 0.49
MAPT P10636 2/20 0.48
HDAC8 Q9BY41 1/20 0.48
KDM4E B2RXH2 3/20 0.47
LMNA P02545 1/20 0.47
HPGD P15428 1/20 0.47
HSD17B10 Q99714 1/20 0.47
APEX1 P27695 1/20 0.47
TAAR1 Q96RJ0 1/20 0.46
HTT P42858 1/20 0.45
CYP1A2 P05177 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL550463 0.85 ALDH1A1 (0.56) ALDH1A1ALOX15KMT2AMEN1POLB
SCHEMBL14015339 0.83 ALDH1A1 (0.54) ALDH1A1ALOX15KMT2AMEN1POLB
SCHEMBL4159724 0.81 HPGD (0.53) ALDH1A1KMT2AMEN1POLBLMNA
SCHEMBL12170872 0.81 ALDH1A1 (0.52) ALDH1A1ALOX15KMT2AMEN1POLB
SCHEMBL743064 0.80 ALDH1A1 (0.73) ALDH1A1KMT2APOLBKDM4ELMNA
SCHEMBL1285869 0.80 ALDH1A1 (0.73) ALDH1A1KMT2APOLBKDM4ELMNA
SCHEMBL799662 0.80 KMT2A (0.75) ALDH1A1ALOX15KMT2AMEN1POLB
SCHEMBL1285890 0.80 ALDH1A1 (0.73) ALDH1A1KMT2APOLBKDM4ELMNA
SCHEMBL14398201 0.79 CTSS (0.54) ALDH1A1ALOX15KMT2AMEN1POLB
SCHEMBL34461718 0.79 LMNA (0.51) ALDH1A1ALOX15KMT2AMEN1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6534659-B2 Amidation of an acid anhydride by a compound comprising a nitrogen/sulfur saturated ring, e.g., thiazolidine; odorless corrosion inhibitors for metal; pollution control NIPPON SHOKUBAI CO., LTD. (JP) 2003-03-18 US disclosed
US-20010047096-A1 Amidation of an acid anhydride by a compound comprising a nitrogen/sulfur saturated ring, e.g., thiazolidine; odorless corrosion inhibitors for metal; pollution control NIPPON SHOKUBAI CO., LTD. (JP) 2001-11-29 US disclosed
EP-1149833-A1 Sulfidoamidocarboxylic acids used as corrosion inhibitors Nippon Shokubai Co., Ltd. (JP) 2001-10-31 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010047096-A1 Amidation of an acid anhydride by a compound comprising a nitrogen/sulfur saturated ring, e.g., thiazolidine; odorless corrosion inhibitors for metal; pollution control CTH, TST, SLC7A11 ALDH1A1 1774/4885ALOX15 2828/4885KMT2A 1498/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.