Sugi Predict

Sugi Predict / Compounds / SCHEMBL4159828

SCHEMBL4159828

SCHEMBL4159828

CCCCCC1CCC([C@H]2CC[C@H](C(=O)O)CC2)CC1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PKM P14618 1/20 0.51
▸ TP53 P04637 1/20 0.51
▸ HTT P42858 2/20 0.50
▸ MEN1 O00255 2/20 0.50
▸ KMT2A Q03164 2/20 0.50
▸ CYP1A2 P05177 3/20 0.49
▸ CYP2D6 P10635 1/20 0.49
▸ CYP2C9 P11712 1/20 0.49
▸ CYP2C19 P33261 1/20 0.49
▸ LMNA P02545 2/20 0.46
▸ PLG P00747 1/20 0.46
▸ PLAT P00750 1/20 0.46
▸ POLB P06746 1/20 0.45
▸ HPGD P15428 1/20 0.45
▸ MAPK1 P28482 1/20 0.45
▸ MAPT P10636 2/20 0.44
▸ CCR2 P41597 1/20 0.43
▸ ALOX5 P09917 1/20 0.39
▸ ANPEP P15144 1/20 0.38
▸ ENPEP Q07075 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1961978 1.00 PKM (0.51) PKMTP53HTTMEN1KMT2A
SCHEMBL4159836 1.00 PKM (0.51) PKMTP53HTTMEN1KMT2A
SCHEMBL1961977 1.00 PKM (0.51) PKMTP53HTTMEN1KMT2A
SCHEMBL27748051 0.98 TP53 (0.54) PKMTP53HTTMEN1KMT2A
SCHEMBL27480731 0.98 TP53 (0.54) PKMTP53HTTMEN1KMT2A
SCHEMBL27480730 0.98 TP53 (0.54) PKMTP53HTTMEN1KMT2A
SCHEMBL9746896 0.98 TP53 (0.54) PKMTP53HTTMEN1KMT2A
SCHEMBL9578611 0.98 TP53 (0.54) PKMTP53HTTMEN1KMT2A
SCHEMBL9578607 0.98 TP53 (0.54) PKMTP53HTTMEN1KMT2A
SCHEMBL27748100 0.98 TP53 (0.54) PKMTP53HTTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023224114-A1 LIQUID CRYSTAL ALIGNING AGENT, LIQUID CRYSTAL ALIGNMENT FILM AND LIQUID CRYSTAL DISPLAY ELEMENT 日産化学株式会社 2023-11-23 — — WO disclosed
US-10619098-B2 Ultraviolet light absorbers TRANSITIONS OPTICAL, INC. (US) 2020-04-14 — — US disclosed
EP-3201292-B1 ULTRAVIOLET LIGHT ABSORBERS TRANSITIONS OPTICAL INC (US) 2018-08-01 — — EP disclosed
US-20170275534-A1 ULTRAVIOLET LIGHT ABSORBERS TRANSITIONS OPTICAL, INC. 2017-09-28 — — US disclosed
EP-3201292-A1 ULTRAVIOLET LIGHT ABSORBERS Transitions Optical, Inc. (US) 2017-08-09 — — EP disclosed
US-9441164-B2 Isosorbide derivative, liquid crystal composition, liquid crystal element, and liquid crystal display device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-09-13 — — US disclosed
WO-2016053662-A1 ULTRAVIOLET LIGHT ABSORBERS TRANSITIONS OPTICAL, INC. (US) 2016-04-07 — — WO disclosed
US-20150034868-A1 ISOSORBIDE DERIVATIVE, LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTAL ELEMENT, AND LIQUID CRYSTAL DISPLAY DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-02-05 — — US disclosed
US-8293146-B2 Optical film and phase difference plate, and liquid crystal compound FUJIFILM CORPORATION (JP) 2012-10-23 — — US disclosed
US-20090159857-A1 OPTICAL FILM AND PHASE DIFFERENCE PLATE, AND LIQUID CRYSTAL COMPOUND FUJIFILM CORPORATION (JP) 2009-06-25 — — US disclosed
WO-2007091716-A1 OPTICAL FILM AND PHASE DIFFERENCE PLATE, AND LIQUID CRYSTAL COMPOUND FUJIFILM CORPORATION (JP) 2007-08-16 — — WO disclosed
EP-0393636-A2 Liquid crystal composition and liquid crystal display using said composition CHISSO CORPORATION (JP) 1990-10-24 — — EP disclosed
WO-1990012073-A1 TRIFLUOROMETHYLCYCLOHEXANE DERIVATIVES MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1990-10-18 — — WO disclosed
EP-0332007-A1 Derivatives of 2,3-difluorohydroquinone MERCK PATENT GmbH (DE) 1989-09-13 — — EP disclosed
US-4617140-A Bicyclohexyl derivatives MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1986-10-14 — — US disclosed
US-4323504-A Cyclohexyl cyclohexyl dioxane liquid crystalline compounds and admixture containing same TIMEX CORPORATION (US) 1982-04-06 — — US disclosed
US-4323473-A Cyclohexyl cyclohexyl dioxane liquid crystalline compounds and admixture containing same TIMEX CORPORATION (US) 1982-04-06 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090159857-A1 OPTICAL FILM AND PHASE DIFFERENCE PLATE, AND LIQUID CRYSTAL COMPOUND NOM1, CRYZ, CNN2 PKM 4809/4885TP53 1634/4885HTT 4198/4885
US-10619098-B2 Ultraviolet light absorbers ERCC1, MCM4, ERCC4 PKM 3486/4885TP53 1138/4885HTT 337/4885
US-20170275534-A1 ULTRAVIOLET LIGHT ABSORBERS MCM4, ERCC1, ERCC4 PKM 4025/4885TP53 2008/4885HTT 256/4885
US-20150034868-A1 ISOSORBIDE DERIVATIVE, LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTAL ELEMENT, AND LIQUID CRYSTAL DISPLAY DEVICE AR, NR3C2, RCC2 PKM 3255/4885TP53 2936/4885HTT 4133/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.