Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 6/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 6/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 6/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA7 | P43166 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.34 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.34 |
| ▸ | GABRP | O00591 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4154404 | 0.88 | PTGER1 (0.54) | PTGER1SMN1; SMN2GABRG2GABRB3GABRA5 | |
| SCHEMBL5619593 | 0.82 | CYP2C9 (0.43) | PTGER1SMN1; SMN2LMNACA12CA1 | |
| SCHEMBL4155974 | 0.80 | PTGER1 (0.37) | PTGER1 | |
| SCHEMBL4147556 | 0.80 | SMN1; SMN2 (0.41) | PTGER1ALDH1A1SMN1; SMN2GABRG2GABRB3 | |
| SCHEMBL4154407 | 0.78 | CYP1A2 (0.47) | PTGER1ALDH1A1SMN1; SMN2GABRG2GABRB3 | |
| SCHEMBL4146588 | 0.78 | MAPT (0.41) | PTGER1ALDH1A1SMN1; SMN2LMNACA12 | |
| SCHEMBL4922618 | 0.76 | CYP1A2 (0.47) | PTGER1ALDH1A1SMN1; SMN2GABRG2GABRB3 | |
| SCHEMBL4158410 | 0.73 | GABRG2 (0.38) | PTGER1ALDH1A1SMN1; SMN2GABRG2GABRB3 | |
| SCHEMBL4149780 | 0.71 | PTGER1 (0.82) | PTGER1 | |
| SCHEMBL5619860 | 0.71 | PTGER1 (0.47) | PTGER1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090227591-A1 | Cyclopentene compounds | GLAXO GROUP LIMITED (GB) | 2009-09-10 | — | — | US | disclosed |
| US-20090227591-A1 | Cyclopentene compounds | GLAXO GROUP LIMITED (GB) | 2009-09-10 | — | — | US | disclosed |
| US-20090227591-A1 | Cyclopentene compounds | GLAXO GROUP LIMITED (GB) | 2009-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090227591-A1 | Cyclopentene compounds | C1R, CYP1B1, ADORA2B | PTGER1 246/4885ALDH1A1 1534/4885SMN1; SMN2 3323/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.