Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TOP1 | P11387 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13998446 | 1.00 | PDE4A (0.58) | PDE4ALMNAL3MBTL1TDP1USP2 | |
| SCHEMBL13998326 | 1.00 | PDE4A (0.58) | PDE4ALMNAL3MBTL1TDP1USP2 | |
| SCHEMBL8083544 | 1.00 | PDE4A (0.58) | PDE4ALMNAL3MBTL1TDP1USP2 | |
| SCHEMBL29756403 | 1.00 | PDE4A (0.58) | PDE4ALMNAL3MBTL1TDP1USP2 | |
| SCHEMBL9965102 | 1.00 | PDE4A (0.58) | PDE4ALMNAL3MBTL1TDP1USP2 | |
| SCHEMBL8095380 | 1.00 | PDE4A (0.58) | PDE4ALMNAL3MBTL1TDP1USP2 | |
| SCHEMBL343766 | 1.00 | PDE4A (0.58) | PDE4ALMNAL3MBTL1TDP1USP2 | |
| Ammonia Solution, Strong SCHEMBL28915080 | 0.98 | PDE4A (0.56) | PDE4ALMNAL3MBTL1TDP1USP2 | |
| SCHEMBL15239580 | 0.93 | PDE4A (0.48) | PDE4ALMNAL3MBTL1TDP1USP2 | |
| SCHEMBL13879019 | 0.93 | PDE4A (0.48) | PDE4ALMNAL3MBTL1TDP1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102365025-A | Conjugate-based systems for controlled drug delivery | SMARTCELLS INC | 2012-02-29 | — | — | CN | claimed |
| CN-122055379-A | Compounds containing one or more diboronate esters and related insulin analogues | 普罗托莫科技公司 | 2026-05-15 | — | — | CN | disclosed |
| EP-4694932-A2 | COMPOUNDS CONTAINING ONE OR MORE DIBORONATES AND RELATED INSULIN ANALOGS | Protomer Technologies Inc. (US) | 2026-02-18 | — | — | EP | disclosed |
| US-20260021190-A1 | GLUCOSE-RESPONSIVE INSULIN CONJUGATES COMPRISING A PENTA-VALENT SUGAR CLUSTER FOR TREATMENT OF DIABETES | MERCK SHARP & DOHME LLC (US) | 2026-01-22 | — | — | US | disclosed |
| US-12427187-B2 | Glucose-responsive insulin conjugates | MERCK SHARP & DOHME LLC (US) | 2025-09-30 | — | — | US | disclosed |
| EP-4615487-A1 | GLUCOSE-RESPONSIVE INSULIN CONJUGATES COMPRISING A PENTA-VALENT SUGAR CLUSTER FOR TREATMENT OF DIABETES | Merck Sharp & Dohme LLC (US) | 2025-09-17 | — | — | EP | disclosed |
| US-20250249074-A1 | GLUCOSE RESPONSIVE INSULINS | PROTOMER TECHNOLOGIES INC. | 2025-08-07 | — | — | US | disclosed |
| EP-4525919-A1 | AROMATIC BORON-CONTAINING COMPOUNDS AND RELATED INSULIN ANALOGS | Protomer Technologies Inc. (US) | 2025-03-26 | — | — | EP | disclosed |
| CN-119677541-A | Aromatic boron-containing compounds and related insulin analogues | 原聚体科技公司 | 2025-03-21 | — | — | CN | disclosed |
| US-12214018-B2 | Glucose responsive insulins | PROTOMER TECHNOLOGIES, INC. (US) | 2025-02-04 | — | — | US | disclosed |
| EP-1854805-B1 | Coffee-derived surfactants | INTERCONTINENTAL GREAT BRANDS LLC (US) | 2016-06-22 | — | — | EP | disclosed |
| US-20140065282-A1 | Coffee-Derived Surfactants | INTERCONTINENTAL GREAT BRANDS LLC (US) | 2014-03-06 | — | — | US | disclosed |
| US-8603562-B2 | Coffee-derived surfactants | INTERCONTINENTAL GREAT BRANDS LLC (US) | 2013-12-10 | — | — | US | disclosed |
| CN-102365025-A | Conjugate-based systems for controlled drug delivery | SMARTCELLS INC | 2012-02-29 | — | — | CN | disclosed |
| CN-102341409-A | Crystalline insulin-conjugates | SMARTCELLS INC | 2012-02-01 | — | — | CN | disclosed |
| US-20090252850-A1 | Coffee-Derived Surfactants | INTERCONTINENTAL GREAT BRANDS LLC | 2009-10-08 | — | — | US | disclosed |
| EP-1854805-A2 | Coffee-derived surfactants | Kraft Foods Holdings, Inc. (US) | 2007-11-14 | — | — | EP | disclosed |
| US-20070259084-A1 | Coffee-Derived Surfactants | KRAFT FOODS GLOBAL BRANDS LLC | 2007-11-08 | — | — | US | disclosed |
| JP-2000273029-A | HAIR COSMETICS | KANEBO LTD | 2000-10-03 | — | — | JP | disclosed |
| JP-2000273023-A | HAIR CONDITIONING COMPOSITION | KANEBO LTD | 2000-10-03 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12427187-B2 | Glucose-responsive insulin conjugates | GPR119, IRS1, INSR | PDE4A 2529/4885LMNA 4836/4885L3MBTL1 1420/4885 |
| US-20250249074-A1 | GLUCOSE RESPONSIVE INSULINS | GLP1R, GPR119, IAPP | PDE4A 1444/4885LMNA 4196/4885L3MBTL1 2699/4885 |
| US-20260021190-A1 | GLUCOSE-RESPONSIVE INSULIN CONJUGATES COMPRISING A PENTA-VALENT SUGAR CLUSTER FOR TREATMENT OF DIABETES | INSR, GPR119, GLP1R | PDE4A 2286/4885LMNA 4564/4885L3MBTL1 2640/4885 |
| US-12214018-B2 | Glucose responsive insulins | GLP1R, GPR119, IAPP | PDE4A 1411/4885LMNA 4296/4885L3MBTL1 2729/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.