Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.62 |
| ▸ | PI4KA | P42356 | 1/20 | 0.47 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.47 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.47 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.47 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.46 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.46 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | NT5E | P21589 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | AMD1 | P17707 | 2/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13926698 | 0.92 | RXFP1 (0.61) | RXFP1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL24980457 | 0.91 | RXFP1 (0.59) | RXFP1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL4152356 | 0.90 | RXFP1 (0.60) | RXFP1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL13099188 | 0.89 | RXFP1 (0.58) | RXFP1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL13662861 | 0.88 | RXFP1 (0.78) | RXFP1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL5052452 | 0.88 | RXFP1 (0.78) | RXFP1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL11759931 | 0.82 | RXFP1 (0.63) | RXFP1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL24981046 | 0.81 | RXFP1 (0.56) | RXFP1PI4KAPI4K2BPI4K2API4KB | |
| Water SCHEMBL9941081 | 0.80 | RXFP1 (0.61) | RXFP1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL15390016 | 0.80 | RXFP1 (0.61) | RXFP1PI4KAPI4K2BPI4K2API4KB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090048203-A1 | SUBSTITUTED ADENINES AND THE USES THEREOF | ASTRAZENECA AB (SE) | 2009-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090048203-A1 | SUBSTITUTED ADENINES AND THE USES THEREOF | HPRT1, APRT, NUDT1 | RXFP1 2979/4885PI4KA 3581/4885PI4K2B 4436/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.