SCHEMBL4160739

SCHEMBL4160739

CCC(=CC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)C(=O)O

nearest known ligand 0.38

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL346289 1.00 THRB (0.38) THRB
SCHEMBL870675 1.00 THRB (0.38) THRB
SCHEMBL1536996 1.00 THRB (0.38) THRB
SCHEMBL5359965 0.98 THRB (0.34) THRB
SCHEMBL28684995 0.92 THRB (0.31) THRB
SCHEMBL4152655 0.86 THRB (0.35) THRB
SCHEMBL28904768 0.86 THRB (0.35) THRB
SCHEMBL28960329 0.86 THRB (0.35) THRB
SCHEMBL28679070 0.84 GRIK1 (0.32)
SCHEMBL28904773 0.84 THRB (0.32) THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090212467-A1 Expandable Bladder PIRELLI PNEUMATICI S.P.A. (IT) 2009-08-27 US claimed
EP-1841576-A1 EXPANDABLE BLADDER Pirelli Tyre S.p.A. (IT) 2007-10-10 EP claimed
WO-2006079359-A1 EXPANDABLE BLADDER PIRELLI TYRE S.P.A. (IT) 2006-08-03 WO claimed
US-20090212467-A1 Expandable Bladder PIRELLI PNEUMATICI S.P.A. (IT) 2009-08-27 US disclosed
EP-1841576-A1 EXPANDABLE BLADDER Pirelli Tyre S.p.A. (IT) 2007-10-10 EP disclosed
WO-2006079359-A1 EXPANDABLE BLADDER PIRELLI TYRE S.P.A. (IT) 2006-08-03 WO disclosed
EP-0473148-A1 Water-dilutable copolymer, its preparation and its use and aqueous coating composition Herberts Gesellschaft mit beschränkter Haftung (DE) 1992-03-04 EP disclosed