SCHEMBL4152655

SCHEMBL4152655

CCCC(=CC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)C(=O)O

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.35
FFAR3 O14843 1/20 0.31
HDAC3 O15379 1/20 0.31
HDAC1 Q13547 1/20 0.31
HDAC2 Q92769 1/20 0.31
HDAC8 Q9BY41 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28904768 1.00 THRB (0.35) THRBFFAR3HDAC3HDAC1HDAC2
SCHEMBL28960329 1.00 THRB (0.35) THRBFFAR3HDAC3HDAC1HDAC2
SCHEMBL28904773 0.98 THRB (0.32) THRBFFAR3HDAC3HDAC1HDAC2
SCHEMBL4152012 0.87 FAAH (0.42)
SCHEMBL870675 0.86 THRB (0.38) THRB
SCHEMBL4160739 0.86 THRB (0.38) THRB
SCHEMBL1536996 0.86 THRB (0.38) THRB
SCHEMBL346289 0.86 THRB (0.38) THRB
SCHEMBL5359965 0.84 THRB (0.34) THRB
SCHEMBL28254636 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090212467-A1 Expandable Bladder PIRELLI PNEUMATICI S.P.A. (IT) 2009-08-27 US claimed
EP-1841576-A1 EXPANDABLE BLADDER Pirelli Tyre S.p.A. (IT) 2007-10-10 EP claimed
WO-2006079359-A1 EXPANDABLE BLADDER PIRELLI TYRE S.P.A. (IT) 2006-08-03 WO claimed
US-20090212467-A1 Expandable Bladder PIRELLI PNEUMATICI S.P.A. (IT) 2009-08-27 US disclosed
US-7544461-B2 Near infrared ray activation type positive resin composition KANSAI PAINT CO., LTD. (JP) 2009-06-09 US disclosed
EP-1841576-A1 EXPANDABLE BLADDER Pirelli Tyre S.p.A. (IT) 2007-10-10 EP disclosed
WO-2006079359-A1 EXPANDABLE BLADDER PIRELLI TYRE S.P.A. (IT) 2006-08-03 WO disclosed