SCHEMBL4160758

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4161987	0.84	AR (0.60)	ARNR3C1PGRNR3C2SLC6A2
	SCHEMBL4165013	0.83	MAOB (0.56)	SLC6A2CYP2D6CYP1A2MTORADRB2
	SCHEMBL4155418	0.80	AR (0.58)	ARNR3C1PGRNR3C2SLC6A2
	SCHEMBL14092267	0.78	NR3C1 (0.79)	ARNR3C1PGRNR3C2HTR1A
	SCHEMBL4163515	0.76	AR (0.55)	ARNR3C1PGRNR3C2SLC6A2
	SCHEMBL4042552	0.76	AR (0.55)	ARNR3C1PGRNR3C2MAPT
	SCHEMBL4151132	0.76	AR (0.58)	ARNR3C1PGRNR3C2MAPT
	SCHEMBL4037187	0.76	MIF (0.67)	ARNR3C1PGRNR3C2MAPT
	SCHEMBL4161563	0.76	AR (0.58)	ARNR3C1PGRNR3C2SLC6A2
	SCHEMBL14092259	0.76	NR3C1 (0.52)	ARNR3C1PGRNR3C2HTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.