SCHEMBL4042552

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14092362	0.88	NR3C1 (0.45)	ARNR3C1PGRNR3C2MAOB
	SCHEMBL28640571	0.84	ALDH1A1 (0.50)	ARMAOBMAOAHSD11B1ALDH1A1
	SCHEMBL4153920	0.81	ERBB2 (0.46)	ARNR3C1PGRNR3C2MAOB
	SCHEMBL30832108	0.80	HSD11B1 (0.72)	MAOBMAOAHSD11B1L3MBTL1MIF
	SCHEMBL8543552	0.80	HSD11B1 (0.72)	MAOBMAOAHSD11B1L3MBTL1MIF
	SCHEMBL14993945	0.80	HSD11B1 (0.72)	MAOBMAOAHSD11B1L3MBTL1MIF
	SCHEMBL8543554	0.80	HSD11B1 (0.72)	MAOBMAOAHSD11B1L3MBTL1MIF
	SCHEMBL4155418	0.80	AR (0.58)	ARNR3C1PGRNR3C2MAOB
	SCHEMBL4163515	0.80	AR (0.55)	ARNR3C1PGRNR3C2MAOB
	SCHEMBL4151132	0.80	AR (0.58)	ARNR3C1PGRNR3C2MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.