Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.59 |
| ▸ | GABRR1 | P24046 | 4/20 | 0.47 |
| ▸ | GABRR2 | P28476 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 5/20 | 0.43 |
| ▸ | PPARG | P37231 | 6/20 | 0.40 |
| ▸ | PPARD | Q03181 | 6/20 | 0.40 |
| ▸ | PPARA | Q07869 | 6/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | TLR2 | O60603 | 2/20 | 0.40 |
| ▸ | FABP4 | P15090 | 2/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.40 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.40 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10884586 | 1.00 | ALOX5 (0.59) | ALOX5GABRR1GABRR2ALDH1A1S1PR3 | |
| SCHEMBL17779535 | 1.00 | ALOX5 (0.59) | ALOX5GABRR1GABRR2ALDH1A1S1PR3 | |
| SCHEMBL417928 | 1.00 | ALOX5 (0.59) | ALOX5GABRR1GABRR2ALDH1A1S1PR3 | |
| SCHEMBL3491458 | 1.00 | ALOX5 (0.59) | ALOX5GABRR1GABRR2ALDH1A1S1PR3 | |
| SCHEMBL11213402 | 1.00 | ALOX5 (0.59) | ALOX5GABRR1GABRR2ALDH1A1S1PR3 | |
| SCHEMBL11414522 | 1.00 | ALOX5 (0.59) | ALOX5GABRR1GABRR2ALDH1A1S1PR3 | |
| SCHEMBL24354392 | 1.00 | ALOX5 (0.59) | ALOX5GABRR1GABRR2ALDH1A1S1PR3 | |
| SCHEMBL301664 | 1.00 | ALOX5 (0.59) | ALOX5GABRR1GABRR2ALDH1A1S1PR3 | |
| SCHEMBL17779527 | 1.00 | ALOX5 (0.59) | ALOX5GABRR1GABRR2ALDH1A1S1PR3 | |
| SCHEMBL21972780 | 1.00 | ALOX5 (0.59) | ALOX5GABRR1GABRR2ALDH1A1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7754675-B2 | 2-heptylcyclopropyl-1-carboxylic acid | SYMRISE GMBH & CO. KG (DE) | 2010-07-13 | — | — | US | claimed |
| US-20060128603-A1 | 2-heptylcyclopropyl-1-carboxylic acid | SYMRISE GMBH & CO. KG (DE) | 2006-06-15 | — | — | US | claimed |
| EP-1565423-B1 | 2-HEPTYLCYCLOPROPYL-1-CARBOXYLIC ACID | SYMRISE GMBH & CO KG (DE) | 2006-06-07 | — | — | EP | claimed |
| EP-3800179-A1 | SALTS OR CO-CRYSTALS OF 3-(3-DIMETHYLAMINO-1-ETHYL-2-METHYL-PROPYL)-PHENOL | Grünenthal GmbH (DE) | 2021-04-07 | — | — | EP | disclosed |
| EP-3656765-A1 | SALTS OR CO-CRYSTALS OF 3-(3-DIMETHYLAMINO-1-ETHYL-2-METHYL-PROPYL)-PHENOL | Grünenthal GmbH (DE) | 2020-05-27 | — | — | EP | disclosed |
| EP-3653600-A1 | SALTS OR CO-CRYSTALS OF 3-(3-DIMETHYLAMINO-1-ETHYL-2-METHYL-PROPYL)-PHENOL | Grünenthal GmbH (DE) | 2020-05-20 | — | — | EP | disclosed |
| EP-3650439-A1 | SALTS OR CO-CRYSTALS OF 3-(3-DIMETHYLAMINO-1-ETHYL-2-METHYL-PROPYL)-PHENOL | Grünenthal GmbH (DE) | 2020-05-13 | — | — | EP | disclosed |
| EP-3636629-A1 | SALTS OR CO-CRYSTALS OF 3-(3-DIMETHYLAMINO-1-ETHYL-2-METHYL-PROPYL)-PHENOL | Grünenthal GmbH (DE) | 2020-04-15 | — | — | EP | disclosed |
| EP-3287447-A1 | SALTS OR CO-CRYSTALS OF 3-(3-DIMETHYLAMINO-1-ETHYL-2-METHYL-PROPYL)-PHENOL | Grünenthal GmbH (DE) | 2018-02-28 | — | — | EP | disclosed |
| CN-106831456-A | The salt or eutectic of 3 (methyl-propyl of 3 dimethylamino, 1 ethyl 2) phenol | 格吕伦塔尔有限公司 | 2017-06-13 | — | — | CN | disclosed |
| CN-105218386-A | The salt of 3-(3-dimethylamino-1-Ethyl-2-Methyl-propyl group)-phenol or eutectic | GRUENENTHAL GMBH | 2016-01-06 | — | — | CN | disclosed |
| US-9133142-B2 | Salts or co-crystals of 3-(3-dimethylamino-1-ethyl-2-methyl-propyl)-phenol | GRUENENTHAL GMBH (DE) | 2015-09-15 | — | — | US | disclosed |
| CN-103153971-A | Salts or co-crystals of 3- (3-dimethylamino-1-ethyl-2-methyl-propyl) -phenol | GRUENENTHAL GMBH | 2013-06-12 | — | — | CN | disclosed |
| EP-2595971-A1 | SALTS OR CO-CRYSTALS OF 3-(3-DIMETHYLAMINO-1-ETHYL-2-METHYL-PROPYL)-PHENOL | Grünenthal GmbH (DE) | 2013-05-29 | — | — | EP | disclosed |
| US-20120022117-A1 | Salts or Co-Crystals of 3-(3-dimethylamino-1-ethyl-2-methyl-propyl)-phenol | GRUENENTHAL GMBH (DE) | 2012-01-26 | — | — | US | disclosed |
| WO-2012010316-A1 | SALTS OR CO-CRYSTALS OF 3-(3-DIMETHYLAMINO-1-ETHYL-2-METHYL-PROPYL)-PHENOL | Grünenthal GmbH (DE) | 2012-01-26 | — | — | WO | disclosed |
| US-7754675-B2 | 2-heptylcyclopropyl-1-carboxylic acid | SYMRISE GMBH & CO. KG (DE) | 2010-07-13 | — | — | US | disclosed |
| US-7754675-B2 | 2-heptylcyclopropyl-1-carboxylic acid | SYMRISE GMBH & CO. KG (DE) | 2010-07-13 | — | — | US | disclosed |
| US-20060128603-A1 | 2-heptylcyclopropyl-1-carboxylic acid | SYMRISE GMBH & CO. KG (DE) | 2006-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120022117-A1 | Salts or Co-Crystals of 3-(3-dimethylamino-1-ethyl-2-methyl-propyl)-phenol | RCC2, EP300, SIGMAR1 | ALOX5 2616/4885GABRR1 3659/4885GABRR2 3915/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.