Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 19/20 | 0.91 |
| ▸ | MAP3K20 | Q9NYL2 | 8/20 | 0.91 |
| ▸ | TGFBR2 | P37173 | 8/20 | 0.74 |
| ▸ | THRB | P10828 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL373761 | 0.95 | TGFBR1 (1.00) | TGFBR1MAP3K20TGFBR2THRB | |
| SCHEMBL373883 | 0.93 | TGFBR1 (1.00) | TGFBR1MAP3K20TGFBR2THRB | |
| SCHEMBL372680 | 0.86 | TGFBR1 (1.00) | TGFBR1MAP3K20TGFBR2THRB | |
| SCHEMBL373377 | 0.85 | TGFBR1 (1.00) | TGFBR1MAP3K20TGFBR2THRB | |
| SCHEMBL373725 | 0.84 | TGFBR1 (1.00) | TGFBR1MAP3K20TGFBR2THRB | |
| SCHEMBL31060212 | 0.84 | TGFBR1 (1.00) | TGFBR1MAP3K20TGFBR2THRB | |
| SCHEMBL373236 | 0.84 | TGFBR1 (1.00) | TGFBR1MAP3K20TGFBR2THRB | |
| SCHEMBL373531 | 0.84 | TGFBR1 (1.00) | TGFBR1MAP3K20TGFBR2THRB | |
| SCHEMBL4815067 | 0.81 | TGFBR1 (0.74) | TGFBR1MAP3K20TGFBR2THRB | |
| SCHEMBL373309 | 0.78 | TGFBR1 (1.00) | TGFBR1MAP3K20TGFBR2THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8871744-B2 | Compounds and methods for selectively targeting tumor-associated mucins | B & G Partyers, LLC (US) | 2014-10-28 | — | — | US | disclosed |
| US-20120022016-A1 | Compounds and methods for selectively targeting tumor-associated mucins | B&G PARTNERS, LLC | 2012-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120022016-A1 | Compounds and methods for selectively targeting tumor-associated mucins | MUC1, NEU4, ALK | TGFBR1 1324/4885MAP3K20 2119/4885TGFBR2 1798/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.