SCHEMBL416253

SCHEMBL416253

O=C(O)CCC#CC#CCCC(=O)O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HMGCR P04035 5/20 0.52
PTPN7 P35236 4/20 0.52
LMNA P02545 3/20 0.47
ALKBH5 Q6P6C2 1/20 0.47
SUCNR1 Q9BXA5 1/20 0.47
EGLN1 Q9GZT9 1/20 0.47
SLC22A6 Q4U2R8 1/20 0.42
TSHR P16473 2/20 0.40
NFKB1 P19838 1/20 0.40
PMP22 Q01453 1/20 0.40
EPHX2 P34913 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2D6 P10635 1/20 0.39
MAPT P10636 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
HSD17B10 Q99714 1/20 0.39
FFAR3 O14843 1/20 0.38
HDAC3 O15379 1/20 0.38
HDAC1 Q13547 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4241662 0.97 HMGCR (0.50) HMGCRPTPN7LMNAALKBH5SUCNR1
SCHEMBL3670058 0.87 HMGCR (0.53) HMGCRPTPN7LMNAALKBH5SUCNR1
SCHEMBL5394804 0.87 HMGCR (0.59) HMGCRPTPN7SLC22A6TSHREPHX2
SCHEMBL4972079 0.87 LMNA (0.53) HMGCRPTPN7LMNAALKBH5SUCNR1
SCHEMBL28992298 0.85 HMGCR (0.57) HMGCRPTPN7SLC22A6TSHREPHX2
SCHEMBL17514314 0.84
SCHEMBL30629431 0.83 HMGCR (0.78) HMGCRPTPN7SLC22A6TSHREPHX2
SCHEMBL631018 0.82 PTPN7 (0.72) HMGCRPTPN7LMNASLC22A6TSHR
SCHEMBL414690 0.82 HMGCR (0.81) HMGCRPTPN7SLC22A6TSHREPHX2
Hydrochloric Acid SCHEMBL8451997 0.80 PTPN7 (0.69) HMGCRPTPN7LMNASLC22A6TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9163307-B2 Three-dimensional photoresists via functionalization of polymer thin films fabricated by iCVD MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2015-10-20 US claimed
US-20130260054-A1 Three-Dimensional Photoresists via Functionalization of Polymer Thin Films Fabricated by iCVD MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2013-10-03 US claimed
WO-2013148126-A1 THREE-DIMENSIONAL PHOTORESISTS VIA FUNCTIONALIZATION OF POLYMER THIN FILMS FABRICATED BY ICVD MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2013-10-03 WO claimed
JP-5032584-A None JP disclosed
US-20250248395-A1 ANTIMICROBIAL POROUS FRAMEWORKS THE UNIVERSITY OF BRISTOL (GB) 2025-08-07 US disclosed
CN-119013329-A Antimicrobial porous framework 布里斯托尔大学 2024-11-22 CN disclosed
WO-2023199058-A1 ANTIMICROBIAL POROUS FRAMEWORKS THE UNIVERSITY OF BRISTOL (GB) 2023-10-19 WO disclosed
US-11504991-B2 Inkless printing on substrates and comestibles INTERCONTINENTAL GREAT BRANDS LLC (US) 2022-11-22 US disclosed
CN-114536885-A Packaging material containing indicator responsive to external stimulus 洲际大品牌有限责任公司 2022-05-27 CN disclosed
US-20200247167-A1 INKLESS PRINTING ON SUBSTRATES AND COMESTIBLES MONDELEZ UK R&D LIMITED (GB) 2020-08-06 US disclosed
US-20200232958-A1 PACKAGING MATERIAL COMPRISING INDICATOR RESPONDING TO AN EXTERNAL STIMULUS INTERCONTINENTAL GREAT BRANDS LLC 2020-07-23 US disclosed
WO-2004110876-A2 CO2 GENERATING ABSORBENT PADS CO2 TECHNOLOGIES, INC. (US) 2004-12-23 WO disclosed
US-20040247750-A1 CO2 generating absorbent pads CO2 TECHNOLOGIES, INC. 2004-12-09 US disclosed
US-6797235-B2 Device and methods for modifying an atmosphere CO2 TECHNOLOGIES, INC. 2004-09-28 US disclosed
US-20040047760-A1 Device and methods for modifying an atmosphere LONGER SHELF LIFE, LLC 2004-03-11 US disclosed
JP-H0532584-A PRODUCTION OF TETRAENEDICARBOXYLIC ACID SHISEIDO CO LTD 1993-02-09 JP disclosed
US-4946919-A HIGH CONCENTRATION OF BORON FROM PYROLYSIS OF ALKYNE-OR DIYNEDIOL-BASED BORON-CONTAING ADDITION POLYMERS OR POLYESTERS HOECHST CELANESE CORP. (US) 1990-08-07 US disclosed
US-4857490-A Process of manufacturing boron ceramics from carboralated diacetylene polymers HOECHST CELANESE CORP. (US) 1989-08-15 US disclosed
EP-0042069-B1 METAL SALTS OF POLYACETYLENIC COMPOUNDS AND USES THEREOF ALLIED CORPORATION (US) 1985-02-06 EP disclosed
US-4373032-A Metal salts of polyacetylenic compounds and uses thereof as ion exchange and thermochromic polymers ALLIED CORPORATION (US) 1983-02-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250248395-A1 ANTIMICROBIAL POROUS FRAMEWORKS MAVS, PUF60, SEPTIN8 HMGCR 4313/4885PTPN7 4555/4885LMNA 4132/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.