Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 8/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4162608 | 0.93 | PTGER1 (0.44) | PTGER1CYP2C9MRGPRX4THRBALDH1A1 | |
| SCHEMBL4162898 | 0.91 | PTGER1 (0.44) | PTGER1CYP2C9ALDH1A1POLBCYP3A4 | |
| SCHEMBL4159296 | 0.90 | PTGER1 (0.44) | PTGER1CYP2C9MRGPRX4CYP3A4CYP2C19 | |
| SCHEMBL4164430 | 0.89 | PTGER1 (0.42) | PTGER1CYP2C9ALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL4150643 | 0.88 | PTGER1 (0.46) | PTGER1CYP2C9THRBALDH1A1GAA | |
| SCHEMBL4149701 | 0.88 | MRGPRX4 (0.39) | PTGER1CYP2C9MRGPRX4THRBALDH1A1 | |
| SCHEMBL4157969 | 0.86 | MRGPRX4 (0.42) | PTGER1CYP2C9MRGPRX4THRBCYP3A4 | |
| SCHEMBL4150598 | 0.86 | PTGER1 (0.46) | PTGER1CYP2C9ALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL4149183 | 0.85 | PTGER1 (0.49) | PTGER1CYP2C9MRGPRX4MEN1KMT2A | |
| SCHEMBL4149233 | 0.85 | PTGS2 (0.38) | PTGER1CYP2C9MRGPRX4THRBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090227591-A1 | Cyclopentene compounds | GLAXO GROUP LIMITED (GB) | 2009-09-10 | — | — | US | disclosed |
| US-20090227591-A1 | Cyclopentene compounds | GLAXO GROUP LIMITED (GB) | 2009-09-10 | — | — | US | disclosed |
| US-20090227591-A1 | Cyclopentene compounds | GLAXO GROUP LIMITED (GB) | 2009-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090227591-A1 | Cyclopentene compounds | C1R, CYP1B1, ADORA2B | PTGER1 246/4885CYP2C9 5/4885MRGPRX4 435/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.