Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 10/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 10/20 | 0.56 |
| ▸ | CYP19A1 | P11511 | 10/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 9/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 8/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11937116 | 0.84 | CYP3A4 (0.56) | RAB9ASMN1; SMN2LMNAHPGDPOLB | |
| SCHEMBL14424586 | 0.83 | CYP2D6 (0.55) | RAB9ASMN1; SMN2LMNAHPGDPOLB | |
| SCHEMBL418165 | 0.78 | KDM4E (0.51) | RAB9ASMN1; SMN2HPGDALDH1A1NPC1 | |
| SCHEMBL416455 | 0.77 | HSD11B1 (0.51) | RAB9ASMN1; SMN2LMNAHPGDCYP3A4 | |
| SCHEMBL6954855 | 0.74 | CYP2D6 (0.56) | RAB9ASMN1; SMN2LMNAHPGDPOLB | |
| SCHEMBL30311943 | 0.74 | CYP2D6 (0.60) | RAB9ASMN1; SMN2LMNAHPGDPOLB | |
| SCHEMBL9151170 | 0.74 | CYP2D6 (0.76) | RAB9ASMN1; SMN2CYP2C9CYP2C19CYP19A1 | |
| SCHEMBL5583851 | 0.74 | CYP2D6 (0.76) | RAB9ASMN1; SMN2CYP2C9CYP2C19CYP19A1 | |
| SCHEMBL417139 | 0.73 | NISCH (0.45) | RAB9ASMN1; SMN2LMNAHPGDPOLB | |
| SCHEMBL4723390 | 0.72 | CYP2D6 (1.00) | RAB9ASMN1; SMN2LMNAHPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120022083-A1 | SMALL MOLECULE MODULATORS OF CELL ADHESION | ADHEREX TECHNOLOGIES, INC. (CA) | 2012-01-26 | — | — | US | claimed |
| US-20090291967-A1 | SMALL MOLECULE MODULATORS OF CELL ADHESION | ADHEREX TECHNOLOGIES, INC. (CA) | 2009-11-26 | — | — | US | claimed |
| US-20120022083-A1 | SMALL MOLECULE MODULATORS OF CELL ADHESION | ADHEREX TECHNOLOGIES, INC. (CA) | 2012-01-26 | — | — | US | disclosed |
| US-20120022083-A1 | SMALL MOLECULE MODULATORS OF CELL ADHESION | ADHEREX TECHNOLOGIES, INC. (CA) | 2012-01-26 | — | — | US | disclosed |
| US-20120022083-A1 | SMALL MOLECULE MODULATORS OF CELL ADHESION | ADHEREX TECHNOLOGIES, INC. (CA) | 2012-01-26 | — | — | US | disclosed |
| US-20090291967-A1 | SMALL MOLECULE MODULATORS OF CELL ADHESION | ADHEREX TECHNOLOGIES, INC. (CA) | 2009-11-26 | — | — | US | disclosed |
| US-20090291967-A1 | SMALL MOLECULE MODULATORS OF CELL ADHESION | ADHEREX TECHNOLOGIES, INC. (CA) | 2009-11-26 | — | — | US | disclosed |
| US-20090291967-A1 | SMALL MOLECULE MODULATORS OF CELL ADHESION | ADHEREX TECHNOLOGIES, INC. (CA) | 2009-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090291967-A1 | SMALL MOLECULE MODULATORS OF CELL ADHESION | CDH1, EPCAM, ICAM1 | RAB9A 100/4885SMN1; SMN2 4029/4885LMNA 1422/4885 |
| US-20120022083-A1 | SMALL MOLECULE MODULATORS OF CELL ADHESION | CDH1, EPCAM, ICAM1 | RAB9A 100/4885SMN1; SMN2 4029/4885LMNA 1422/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.