Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4168887 | 0.83 | — | — | |
| SCHEMBL4155956 | 0.79 | CYP2A6 (0.31) | — | |
| SCHEMBL4166529 | 0.76 | CYP1A2 (0.50) | — | |
| Bromide SCHEMBL4161301 | 0.75 | CYP1A2 (0.49) | — | |
| SCHEMBL25616004 | 0.64 | CYP4F2 (0.33) | — | |
| SCHEMBL4019278 | 0.64 | CYP4F2 (0.34) | PDK2 | |
| SCHEMBL17414233 | 0.63 | PDK2 (0.44) | PDK2EPAS1 | |
| SCHEMBL11319543 | 0.63 | PDK2 (0.37) | PDK2EPAS1 | |
| SCHEMBL11319176 | 0.63 | CYP1A2 (0.39) | PDK2 | |
| SCHEMBL1057960 | 0.61 | KDM4E (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090069408-A1 | TRICYCLIC COMPOUNDS USEFUL IN TREATING IRON DISORDERS | XENON PHARMACEUTICALS INC. (CA) | 2009-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069408-A1 | TRICYCLIC COMPOUNDS USEFUL IN TREATING IRON DISORDERS | TFRC, SLC40A1, FECH | PDK2 2112/4885EPAS1 3845/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.