SCHEMBL416460

SCHEMBL416460

CCC(C(=O)OC)S(N)(=O)=O

nearest known ligand 0.39

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CA1 P00915 7/20 0.39
CA2 P00918 7/20 0.39
CA14 Q9ULX7 3/20 0.39
CA12 O43570 8/20 0.36
CA9 Q16790 7/20 0.36
SMN1; SMN2 Q16637 2/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
ZDHHC7 Q9NXF8 1/20 0.33
CA7 P43166 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28947569 0.80 CA1 (0.41) CA1CA2CA14CA12CA9
SCHEMBL13978750 0.80 CA2 (0.41) CA1CA2CA14CA12CA9
Hydrochloric Acid SCHEMBL28316002 0.78 CA1 (0.39) CA1CA2CA14CA12CA9
SCHEMBL3647648 0.78 CA1 (0.39) CA1CA2CA14CA12CA9
SCHEMBL7330478 0.76 CA1 (0.35) CA1CA2CA14CA12CA9
SCHEMBL25390760 0.75 CA1 (0.37) CA1CA2CA14CA7
SCHEMBL3790269 0.75 GCLC (0.37) CA1CA2CA14CA7
SCHEMBL19285532 0.74 KMT2A (0.39) CA2CA14CA9SMN1; SMN2MEN1
SCHEMBL28063951 0.71 GCLC (0.35) CA1CA2
Sulfuric Acid SCHEMBL29010532 0.70 CA1 (0.39) CA1CA2CA14CA12CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106518850-B A kind of chemical synthesis process of pimobendan 青岛农业大学 2019-04-09 CN claimed
US-20130012432-A1 Peptides for Treatment of Obesity NOVO NORDISK A/S (DK) 2013-01-10 US disclosed
EP-2539364-A1 PEPTIDES FOR TREATMENT OF OBESITY Novo Nordisk A/S (DK) 2013-01-02 EP disclosed
US-20120021973-A1 Peptides for Treatment of Obesity NOVO NORDISK A/S (DK) 2012-01-26 US disclosed
CN-102223898-A Peptides for treatment of obesity NOVO NORDISK AS 2011-10-19 CN disclosed
EP-2370104-A1 PEPTIDES FOR TREATMENT OF OBESITY Novo Nordisk A/S (DK) 2011-10-05 EP disclosed
WO-2011104378-A1 PEPTIDES FOR TREATMENT OF OBESITY NOVO NORDISK A/S (DK) 2011-09-01 WO disclosed
US-20100173835-A1 Peptides for Treatment of Obesity NOVO NORDISK A/S (DK) 2010-07-08 US disclosed
WO-2010060901-A1 PEPTIDES FOR TREATMENT OF OBESITY NOVO NORDISK A/S (DK) 2010-06-03 WO disclosed
US-20100056433-A1 Novel Peptides for Use in the Treatment of Obesity NOVO NORDISK A/S (DK) 2010-03-04 US disclosed
EP-2104684-A1 PEPTIDES FOR USE IN THE TREATMENT OF OBESITY Novo Nordisk A/S (DK) 2009-09-30 EP disclosed
EP-2101822-A2 USE OF PEPTIDES IN COMBINATION WITH SURGICAL INTERVENTION FOR THE TREATMENT OF OBESITY Novo Nordisk A/S (DK) 2009-09-23 EP disclosed
US-20090203581-A1 Novel Peptides for Use in the Treatment of Obesity NOVO NORDISK A/S (DK) 2009-08-13 US disclosed
WO-2008087186-A2 PEPTIDES FOR USE IN THE TREATMENT OF OBESITY NOVO NORDISK A/S (DK) 2008-07-24 WO disclosed
WO-2008087189-A2 PEPTIDES FOR USE IN THE TREATMENT OF OBESITY NOVO NORDISK A/S (DK) 2008-07-24 WO disclosed
WO-2008087190-A2 USE OF PEPTIDES IN COMBINATION WITH SURGICAL INTERVENTION FOR THE TREATMENT OF OBESITY NOVO NORDISK A/S (DK) 2008-07-24 WO disclosed
WO-2008087187-A1 PEPTIDES FOR USE IN THE TREATMENT OF OBESITY NOVO NORDISK A/S (DK) 2008-07-24 WO disclosed
WO-2008087188-A2 PEPTIDES FOR USE IN THE TREATMENT OF OBESITY NOVO NORDISK A/S (DK) 2008-07-24 WO disclosed
EP-1907010-A2 PEPTIDES FOR USE IN THE TREATMENT OF OBESITY Novo Nordisk A/S (DK) 2008-04-09 EP disclosed
WO-2007009894-A2 PEPTIDES FOR USE IN THE TREATMENT OF OBESITY NOVO NORDISK A/S (DK) 2007-01-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120021973-A1 Peptides for Treatment of Obesity MC4R, GIPR, MC3R CA1 4462/4885CA2 2853/4885CA14 3242/4885
US-20090203581-A1 Novel Peptides for Use in the Treatment of Obesity MC4R, MC3R, GIPR CA1 4460/4885CA2 3110/4885CA14 2761/4885
US-20100173835-A1 Peptides for Treatment of Obesity MC4R, GIPR, MC3R CA1 4462/4885CA2 2853/4885CA14 3242/4885
US-20100056433-A1 Novel Peptides for Use in the Treatment of Obesity MC4R, MC3R, GIPR CA1 4460/4885CA2 3110/4885CA14 2761/4885
US-20130012432-A1 Peptides for Treatment of Obesity MC4R, GIPR, MC3R CA1 4462/4885CA2 2853/4885CA14 3242/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.