Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.34 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.33 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 3/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | GSR | P00390 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.30 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.30 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.30 |
| ▸ | ANPEP | P15144 | 1/20 | 0.30 |
| ▸ | EPOR | P19235 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL416460 | 0.76 | CA1 (0.39) | CA1CA2CA14ZDHHC7CA12 | |
| SCHEMBL19285532 | 0.75 | KMT2A (0.39) | CA2CA14CA9MEN1KMT2A | |
| SCHEMBL18929976 | 0.73 | CA14 (0.36) | CA1CA2CA14ZDHHC7CA12 | |
| SCHEMBL569593 | 0.72 | GSR (0.48) | CA1CA2CPB2ZDHHC7CYP1A2 | |
| SCHEMBL10039149 | 0.72 | GABRR1 (0.41) | CA1CA2CA14CPB2ZDHHC7 | |
| SCHEMBL569592 | 0.72 | GSR (0.48) | CA1CA2CPB2ZDHHC7CYP1A2 | |
| SCHEMBL1518233 | 0.72 | GSR (0.48) | CA1CA2CPB2ZDHHC7CYP1A2 | |
| SCHEMBL14019262 | 0.72 | GABRR1 (0.41) | CA1CA2CA14CPB2ZDHHC7 | |
| SCHEMBL5076556 | 0.72 | CA1 (0.39) | CA1CA2CPB2ZDHHC7CYP1A2 | |
| SCHEMBL7826438 | 0.72 | CA1 (0.39) | CA1CA2CPB2ZDHHC7CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5494925-A | TREATING DEGENERATIVE DISORDERS; PROTEOLYTIC ENZYME INHIBITOR | STERLING WINTHROP INC. (US) | 1996-02-27 | — | — | US | disclosed |