SCHEMBL416481

SCHEMBL416481

[CH2]CCCC(=O)Oc1ccc(O)c(C)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.43
NPC1 O15118 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
ALDH1A1 P00352 3/20 0.43
MAPT P10636 2/20 0.43
KMT2A Q03164 5/20 0.42
LMNA P02545 1/20 0.42
HTT P42858 1/20 0.42
HSD17B10 Q99714 1/20 0.42
KDM4E B2RXH2 1/20 0.41
GLA P06280 1/20 0.41
GAA P10253 1/20 0.41
TP53 P04637 1/20 0.40
ACHE P22303 1/20 0.40
MEN1 O00255 1/20 0.38
SLC22A2 O15244 1/20 0.38
TMPRSS2 O15393 1/20 0.38
F2 P00734 1/20 0.38
F10 P00742 1/20 0.38
PLG P00747 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27667468 0.90 KMT2A (0.47) TDP1NPC1L3MBTL1ALDH1A1MAPT
SCHEMBL9807333 0.88 KMT2A (0.47) TDP1NPC1L3MBTL1ALDH1A1MAPT
SCHEMBL27667469 0.85 GAA (0.43) TDP1NPC1L3MBTL1ALDH1A1MAPT
SCHEMBL29268227 0.84 ALDH1A1 (0.56) TDP1NPC1L3MBTL1ALDH1A1MAPT
SCHEMBL10609755 0.81 BRD4 (0.45) L3MBTL1ALDH1A1KMT2AKDM4EGLA
SCHEMBL2813313 0.80 ACHE (0.59) TDP1NPC1L3MBTL1ALDH1A1KMT2A
SCHEMBL29232710 0.80 APP (0.48) TDP1NPC1L3MBTL1ALDH1A1MAPT
SCHEMBL6897902 0.80 TDP1 (0.42) TDP1NPC1L3MBTL1ALDH1A1MAPT
SCHEMBL9237069 0.76 KMT2A (0.53) ALDH1A1MAPTKMT2ALMNAHTT
SCHEMBL419283 0.76 KMT2A (0.53) TDP1NPC1ALDH1A1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3219506-B1 THERMOSENSITIVE RECORDING MATERIALS CONTAINING CHELATING AGENTS RICOH CO LTD (JP) 2019-11-06 EP disclosed
EP-3287292-B1 THERMOSENSITIVE RECORDING MATERIALS CONTAINING CHELATING AGENTS RICOH CO LTD (JP) 2019-06-19 EP disclosed
EP-3287292-A1 THERMOSENSITIVE RECORDING MATERIALS CONTAINING CHELATING AGENTS Ricoh Company, Ltd. (JP) 2018-02-28 EP disclosed
EP-3219506-A1 THERMOSENSITIVE RECORDING MATERIALS CONTAINING CHELATING AGENTS Ricoh Company, Ltd. (JP) 2017-09-20 EP disclosed
US-8753721-B2 Method and apparatus for producing thermosensitive recording material RICOH COMPANY, LTD. (JP) 2014-06-17 US disclosed
US-8193116-B2 Heat-sensitive recording material RICOH COMPANY, LTD. (JP) 2012-06-05 US disclosed
US-20120021900-A1 HEAT-SENSITIVE RECORDING MATERIAL RICOH COMPANY, LTD. (JP) 2012-01-26 US disclosed
US-20100239766-A1 Method And Apparatus For Producing Thermosensitive Recording Material RICOH COMPANY, LTD. (JP) 2010-09-23 US disclosed