Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.71 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.71 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.71 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.71 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.71 |
| ▸ | MAPT | P10636 | 2/20 | 0.71 |
| ▸ | HPGD | P15428 | 2/20 | 0.71 |
| ▸ | GAA | P10253 | 1/20 | 0.71 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.71 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.64 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclomethyltryptophan SCHEMBL7889282 | 1.00 | KDM4E (0.71) | KDM4ECYP2D6CYP1A2CYP2C9CYP2C19 | |
| Cyclomethyltryptophan SCHEMBL416558 | 1.00 | KDM4E (0.71) | KDM4ECYP2D6CYP1A2CYP2C9CYP2C19 | |
| Cyclomethyltryptophan SCHEMBL29535380 | 1.00 | KDM4E (0.71) | KDM4ECYP2D6CYP1A2CYP2C9CYP2C19 | |
| Cyclomethyltryptophan SCHEMBL10642614 | 0.98 | KDM4E (0.69) | KDM4ECYP2D6CYP1A2CYP2C9CYP2C19 | |
| Cyclomethyltryptophan SCHEMBL28419799 | 0.98 | KDM4E (0.69) | KDM4ECYP2D6CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL12257169 | 0.90 | CYP2D6 (0.58) | KDM4ECYP2D6CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL10639172 | 0.87 | KDM4E (0.69) | KDM4ECYP2D6CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL1877421 | 0.87 | KDM4E (0.69) | KDM4ECYP2D6CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL3110230 | 0.87 | KDM4E (0.73) | KDM4ECYP2D6CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL13840607 | 0.87 | KDM4E (0.73) | KDM4ECYP2D6CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 322 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122005693-A | Application of Jiaweidanzhi Xiaoyao powder or extract thereof in preparation of medicines for treating depression complicated with ulcerative colitis | 河南中医药大学 | 2026-05-12 | — | — | CN | claimed |
| CN-116804040-A | Carboline oral small molecule anti-inflammatory medicament and preparation method and application thereof | 首都医科大学 | 2023-09-26 | — | — | CN | claimed |
| CN-112010914-B | Glucosamine modified pentacyclic piperazine dione and preparation and application thereof | 首都医科大学 | 2023-06-27 | — | — | CN | claimed |
| CN-112010937-B | YIGSR modified pentacyclic piperazinedione and preparation and application thereof | 首都医科大学（CN） | 2023-01-13 | — | — | CN | claimed |
| CN-115490684-A | 3S-1,2,3, 4-tetrahydro-beta-carboline-3-methyl-amino acid, preparation thereof, antithrombotic activity and application thereof | 首都医科大学 | 2022-12-20 | — | — | CN | claimed |
| CN-115490685-A | Tetrahydro-beta-carboline-3-methyl-amino acid, preparation method thereof and application thereof in preparing anti-inflammatory drugs | 首都医科大学 | 2022-12-20 | — | — | CN | claimed |
| CN-115477648-A | Carboline derivative, preparation method thereof and application thereof in preparing antitumor drugs | 首都医科大学 | 2022-12-16 | — | — | CN | claimed |
| CN-115215860-A | Oral small molecule P-selectin inhibitor and preparation method and application thereof | 首都医科大学 | 2022-10-21 | — | — | CN | claimed |
| CN-112010855-B | Hexacyclic piperazinedione compounds, preparation, biological activity and application thereof | 首都医科大学 | 2021-06-08 | — | — | CN | claimed |
| CN-112010935-A | Acetyl RGD modified hexacyclic piperazinedione, preparation, anti-tumor activity and application thereof | 首都医科大学 | 2020-12-01 | — | — | CN | claimed |
| WO-2008087186-A2 | PEPTIDES FOR USE IN THE TREATMENT OF OBESITY | NOVO NORDISK A/S (DK) | 2008-07-24 | — | — | WO | claimed |
| WO-2008087188-A2 | PEPTIDES FOR USE IN THE TREATMENT OF OBESITY | NOVO NORDISK A/S (DK) | 2008-07-24 | — | — | WO | claimed |
| WO-2008087190-A2 | USE OF PEPTIDES IN COMBINATION WITH SURGICAL INTERVENTION FOR THE TREATMENT OF OBESITY | NOVO NORDISK A/S (DK) | 2008-07-24 | — | — | WO | claimed |
| EP-1907010-A2 | PEPTIDES FOR USE IN THE TREATMENT OF OBESITY | Novo Nordisk A/S (DK) | 2008-04-09 | — | — | EP | claimed |
| US-20080039387-A1 | Novel Peptides for Use in the Treatment of Obesity | NOVO NORDISK A/S (DK) | 2008-02-14 | — | — | US | claimed |
| US-20070027091-A1 | Novel Melanocortin Receptor Agonists | NOVO NORDISK A/S (DK) | 2007-02-01 | — | — | US | claimed |
| WO-2007009894-A2 | PEPTIDES FOR USE IN THE TREATMENT OF OBESITY | NOVO NORDISK A/S (DK) | 2007-01-25 | — | — | WO | claimed |
| EP-1670815-A2 | MELANOCORTIN RECEPTOR AGONISTS | NOVO NORDISK A/S (DK) | 2006-06-21 | — | — | EP | claimed |
| US-20050080015-A1 | Carboline-3-carboxylic acid modified related sequences of Ala-Arg-Pro-Ala-Lys, their synthesis and use as thromobolytic agent | GUANGZHOU BAI YUN SHAN PHARMACEUTICAL CO. LTD (CN) | 2005-04-14 | — | — | US | claimed |
| WO-2005030797-A2 | MELANOCORTIN RECEPTOR AGONISTS | NOVO NORDISK A/S (DK) | 2005-04-07 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050080015-A1 | Carboline-3-carboxylic acid modified related sequences of Ala-Arg-Pro-Ala-Lys, their synthesis and use as thromobolytic agent | PEPD, PLAT, CTSL | KDM4E 4372/4885CYP2D6 1931/4885CYP1A2 3042/4885 |
| US-20070027091-A1 | Novel Melanocortin Receptor Agonists | MC4R, MC3R, MC5R | KDM4E 2585/4885CYP2D6 2701/4885CYP1A2 3582/4885 |
| US-20080039387-A1 | Novel Peptides for Use in the Treatment of Obesity | MC4R, MC3R, GIPR | KDM4E 3804/4885CYP2D6 4349/4885CYP1A2 4679/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.