Isoproterenol

Isoproterenol

SCHEMBL4166

CC(C)NC[C@@H](O)c1ccc(O)c(O)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADRB1ADRB2ADRB3

The experimentally established mechanism targets of Isoproterenol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRB2 known ✓ P07550 7/20 1.00
ADRB1 known ✓ P08588 5/20 1.00
ADRB3 known ✓ P13945 5/20 1.00
MAPT P10636 7/20 1.00
TDP1 Q9NUW8 6/20 1.00
KDM4E B2RXH2 6/20 1.00
TSHR P16473 5/20 1.00
MEN1 O00255 5/20 1.00
KMT2A Q03164 5/20 1.00
MAPK1 P28482 4/20 1.00
HSD17B10 Q99714 4/20 1.00
CYP1A2 P05177 4/20 1.00
HIF1A Q16665 4/20 1.00
MTOR P42345 3/20 1.00
CYP3A4 P08684 3/20 1.00
LMNA P02545 2/20 1.00
NFKB1 P19838 2/20 1.00
ALDH1A1 P00352 2/20 1.00
ADORA3 P0DMS8 2/20 1.00
DRD2 P14416 2/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Isoproterenol SCHEMBL29519146 1.00 MAPT (1.00) MAPTADRB2TDP1KDM4EADRB1
Levisoprenaline SCHEMBL29620666 1.00 MAPT (1.00) MAPTADRB2TDP1KDM4EADRB1
Isoproterenol SCHEMBL4165 1.00 MAPT (1.00) MAPTADRB2TDP1KDM4EADRB1
Isoproterenol SCHEMBL29386243 1.00 MAPT (1.00) MAPTADRB2TDP1KDM4EADRB1
Levisoprenaline SCHEMBL250806 1.00 MAPT (1.00) MAPTADRB2TDP1KDM4EADRB1
Isoproterenol SCHEMBL3253794 1.00 MAPT (1.00) MAPTADRB2TDP1KDM4EADRB1
Isoproterenol SCHEMBL7627 0.98 MAPT (1.00) MAPTADRB2TDP1KDM4EADRB1
Levisoprenaline SCHEMBL4745572 0.98 MAPT (1.00) MAPTADRB2TDP1KDM4EADRB1
Isoproterenol SCHEMBL6151626 0.98 MAPT (0.97) MAPTADRB2TDP1KDM4EADRB1
Isoproterenol SCHEMBL3672791 0.98 MAPT (1.00) MAPTADRB2TDP1KDM4EADRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 42095 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122094963-A Cardioprotective lipids and methods of use 2026-05-26 CN claimed
CN-122070940-A Application of Aralar myocardial over-expression virus in preparation of heart failure treatment drugs 南通大学附属医院 2026-05-22 CN claimed
CN-122072262-A Detection method and kit for absolute quantification of multiple neurotransmitters and related metabolites 清华大学 2026-05-22 CN claimed
WO-2026106917-A1 EDIBLE TRANSMUCOSAL DRUG DELIVERY METHOD USING AN INTERMEDIATE CAPSULE AS A TEMPORARY VESSEL BioPhysics Pharma, Inc. (US) 2026-05-21 WO claimed
WO-2026107412-A1 SARCOSPAN MODULATION AND METHODS OF MEAT AND TISSUE CULTURE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2026-05-21 WO claimed
WO-2026106796-A1 SYSTEM AND METHOD FOR THE TREATMENT OF TELOGEN EFFLUVIUM, ANDROGENETIC ALOPECIA, AND OTHER HAIR LOSS DISORDERS FOLLEA INTERNATIONAL (US) 2026-05-21 WO claimed
WO-2026100654-A1 NUCLEIC ACID INTRODUCTION AID, NUCLEIC ACID INTRODUCTION AGENT, AND NUCLEIC ACID INTRODUCTION METHOD 株式会社インファーマシア 2026-05-15 WO claimed
US-20260132115-A1 SUBSTITUTED 3-FLUOROBENZENEPROPANOATE COMPOUND AND PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF, AND USE THEREOF TIANJIN GUDUI BIO PHARM CO LTD (CN) 2026-05-14 US claimed
CN-122012439-A Catechol-O-methyltransferase mutant and preparation method and application thereof 郑州伊美诺生物技术有限公司 2026-05-12 CN claimed
EP-4736841-A1 A MUCOADHESIVE LAYER FOR BUCCAL ADMINISTRATION OF AN ACTIVE PHARMACEUTICAL INGREDIENT IQ medical GmbH (DE) 2026-05-06 EP claimed
US-4275219-A Novel process and intermediates useful in the preparation of sympathomimetic amines INTERX RESEARCH CORPORATION (US) 1981-06-23 US claimed
WO-1981000849-A1 NOVEL PROCESS AND INTERMEDIATES USEFUL IN THE PREPARATION OF SYMPATHOMIMETIC AMINES INTERX RESEARCH CORP (US) 1981-04-02 WO claimed
US-4258062-A ISOPRENALINE ANTAGONISTS EFFECTING HEART RATE AND BLOOD PRESSURE MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1981-03-24 US claimed
US-4235236-A Device for dispensing drug by combined diffusional and osmotic operations ALZA CORPORATION (US) 1980-11-25 US claimed
US-4116949-A WATER-SOLUBLE, PHYSIOLOGICALLY ACTIVE, SYNTHETIC COPOLYPEPTIDES THE REAGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1978-09-26 US claimed
US-4059686-A SODIUM POLYACRYLATE NIPPON KAYAKU KABUSHIKI KAISHA (JA) 1977-11-22 US claimed
US-4038417-A ADRENERGIC STIMULATING AGENTS, ISOPROTERENOL NELSON RESEARCH & DEVELOPMENT COMPANY (US) 1977-07-26 US claimed
US-4034087-A TREATING PROLIFERATIVE SKIN DISEASES WITH 4-BENZYL-2-IMIDAZOLIDONES THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 1977-07-05 US claimed
US-3968245-A Sympathomimetic topical and percutaneous administration with halogenated promoters ALZA CORPORATION (US) 1976-07-06 US claimed
US-3961071-A CARDIOVASCULAR DISORDERS, 1-PHENOXY-2-HYDROXY-3-TERT-BUTYLAMINO PROPANES BOEHRINGER INGELHEIM GMBH (DT) 1976-06-01 US claimed